As the staff prepares for the presidential debates at a North Carolina conference center, a vexing question about a failed attorney-general nomination (amid charges of racial profiling) leads to flashbacks of the administration's first weeks in office. Back then, Toby's marriage to Andrea Wyatt was about to end; now Sam and Charlie are helping him in his effort to reconcile with her. Meanwhile, the Israeli Air Force weighs in on the Qumari matter, and Joey Lucas reports that the president is likely to lose New Hampshire.
Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.
Investigating the death of a rock band singer who had large amounts of cocaine and heroin in her system, the detectives question a former boyfriend who was a disgruntled band mate of her late husband. The prosecuters are hampered by the actions of a retired detective, who worked a case with Briscoe several years back, turned writer whose unconventional research tactics makes him a suspect as well.
Archer spends a night in sickbay with Dr. Phlox after Porthos contracts a deadly virus on the Kreetassan homeworld. Crew members suspect Archer's increased stress level is due to Porthos' illness, but Dr. Phlox suspects it has to do with Archer's repressed sexual tension.
George goes into denial when Max is thought to have dyslexia, and things only get worse when Angie suggests he may have it, too.
Grissom suspects murder, not suicide, when the body of a dwarf is found hanging from a rope high above a stage in a casino hotel where a convention of little people is being held. Across town, Catherine is attacked at a crime scene where a man was murdered during what appears to have been a home robbery.
Dawson finds himself in an awkward situation when he is put between Joey and the intoxicated leading lady of his film. Audrey allows herself to be taken in by another man's charm.
Frasier is surprised to learn that Kenny has never unpacked the boxes in his office because he views all of his jobs as temporary. Roz's younger cousin Jen comes to stay with her for the week. She is extremely cynical and opinionated, and quickly gets on Frasier's nerves.
A little girl disappears at the park, after her father leaves her - or so he thinks - in the care of a friend's nanny for a moment. Connie's brother-in-law is arrested.
Clark has his first run-in with red kryptonite in this exploration of classic Superman mythology, turning immoral when he gets his high-school ring holding a piece of rock. Meanwhile, Lex and his father have some issues to resolve when Lionel starts taking over the manor.
After deciding to work together, Nick and Burton Fallin return to the old offices of Fallin & Associates to create a new firm, Fallin & Fallin. Finally working on equal ground, Nick and Burton's first big client turns out to be Allegheny County Hospital, which is under scrutiny as one of the nurses is arrested and confesses to killing patients in the oncology department during his shifts. The hospital faces several potential lawsuits from the family members of the patients who died. To assemble a strong team of attorneys, Nick and Burton bring in James Mooney to help with the case but soon discover that his grandmother died in that very hospital just a few months earlier. James immediately removes himself from the case but he eventually gives into his desire to fight for the underdogs and tries to find representation for the family members. Meanwhile, Nick is also thrown into a case as a favor to Laurie Solt, where he must defend a child's right to attend an adoption party. This is a concept that Alvin Masterson finds reprehensible, as he believes it treats the children as though they are cattle to be sold at market.
Things get ugly when Lorelai speaks at the high school's career day. To rebel against her conservative mother, Lane does something drastic.
Buffy begins a new job as school counsellor at Sunnydale High. On her first day she encounters a troubled young girl who is convinced she is about to die.
Jim and Cheryl meet the new neighbors and find out that they can hear their conversation through the baby monitor. When the neighbors find out, Jim tries to come up with a story to smooth things over.
A sports-struck Paul lets Bridget do whatever she wants when she starts dating Travis, star basketball player and son of baseball legend Steve Smith. Meanwhile Kerry resents the fact that Paul still thinks of her as a little girl.
Finch is scared about Jack liking Vicki, so he sets her up to look bad, but he's not sure when she'll get him back. Meanwhile, Nina brings in a woman off the street to prove to Jack that he was wrong to hire Vicki. She is worried though when the woman gets lost in the building.
Feeling rejected by Sophie, Brian becomes friends with a rat.
After a high class party girl dies in custody, Woody will face possible charges. Jordan must step up and defend Woody and try to help save his career. Elsewhere Lily is trying to help a little boy.