This pivotal episode brings Renee Palmer to a hybrid-infested hospital where comatose patients are being used as a food source for the Atavus. It is only when Renee is ultimately able to expose these atrocities that the FBI finally takes seriously the threat of the Atavus, who must feed on the life force of humans in order to survive. The FBI pledges to join Renee's crusade to destroy this formidable alien menace before they take over the world.
Determined to rescue his brother, Dar risks death to fulfill three daunting tasks for the spiteful demon Yamira.
Lynn's sister Tanya comes to town to help celebrate the anniversary of Lynn's adoption. Tanya, who is white, has immersed herself in African-American culture. Maya quickly befriends Tanya, but Joan and Toni grow annoyed with her for acting ""too black"" and get into a confrontation with her. Maya and Lynn defend her, but Tanya later takes things too far at the salon. Meanwhile, Joan tries to organize William's bachelor party.
10 year-old Maddie Harrington shows up on Ally's door saying she's her daughter. She's the result of a mixup on the egg bank Ally deposited her eggs ten years ago. Since Maddie's father died six months ago, she's been living with her aunt, who sings TV themes on nightclubs for a living. After a lot of talking, Maddie decides to stay in Boston with Ally on a trial basis until they resolve where she will stay. Meanwhile, Richard takes the case of a man who killed his wife after kicking her in the head when he mistook her for a soccer ball. John doesn't think he'll be able to win the case because he can't litigate, but Richard surprises him when he wins.
Angel and his friends attend a ballet,where Angel realises he saw the exact same dancers on stage 110 years ago.
After Flex's father eats unheatly and gets a heart attack Flex decides to take risk and live his life as the last day everyday. Meanwhile at Breanna's highschool the upcoming Ghetto-Fabulous dance arrives and Arnaz brings his country cousin for a visit. She wants to go to the dance but not until Breanna and Spirit give her a ghetto makeover.
Nikki's biological father visits, sparking a fierce rivalry with her adoptive dad, George, for her affections. Also, Kim competes with Regina over the planning of a luncheon in Nikki's honor.
Carrie starts working at Vogue and finds out from her acerbic editor that she doesn't have a Vogue idea about relationships. Charlotte throws a baby shower for Miranda, but Miranda gets fed up with her after she tries to make the shower too cutesy. Richard asks Samantha for a threesome with a 21-year-old for his birthday.
Juicy guest casting and ingenious plotting enliven an hourlong episode that airs in the plum post-Super Bowl slot. One storyline unfolds at Hal's company picnic, where Lois clashes with a blabby wife and her beleaguered spouse; and Hal runs afoul of his new boss and the big cheese. In Alaska, Francis's scheme to win a bet involves rigging a hockey game that pits loggers vs. a fearsome women's squad led by a blowhard coach.
After Hal is mistaken by his new boss, as that guy's boss, Hal plays along. Malcolm is in a three-legged scavenger hunt with the girl he likes, but becomes upset after he confesses he likes her, and she says she likes another boy. Reese is also the the scavenger hunt, and at first doesn't like the big dumb bully he is with, but they grow to like each other when they bond over beating up the other contestants and stealing their items. Lois continues to balance keeping Dewey intact and dealing with the crazy woman, but now must talk to the husband as well. Francis continues to sabotage his own team, this time on the ice.
Said and Arif go to Warden Glynn about Lalar's murder. Angry and full of rage, Said then confronts White about passing drugs. Unsatisfied with White's response, Said beats White severely, which gets Said thrown in the hole. Chucky Pancamo's condition worsens. On orders from Schillinger, Winthrop gets into a fight with Guenzel. Schillinger goes to with a deal, he'll let Beecher work for him delivering mail to Keller if Beecher has Guenzel transferred to Gen Pop so Schillinger can have him. Keller discovers the feds have compelling evidence linking him to one of the past murders. Meanwhile, Howell makes her move on Keller, Rebadow's ship comes in...for someone else and Hill becomes gravely ill.
The Jackass crew enter the famous Gumball Rally 3000, starting in London and through 12 countries across Europe in a 3000km long only-for-the-rich-or-crazy rally
Manny decides to audition for cheerleading, but Emma believes that cheerleading is sexist. Meanwhile, J.T., Toby, Liberty and Spinner try to win a contest for one million dollars.
Having lost hand control from his bashing, Justin's quits art school (he's lost the fine motor skills needed to hold a brush.) Michael decides to quit the Big Q and risks all to buy a comic book store. Ted ditches his new accounting job to start his own porno website.
After Arnold saves the life of a rich man, the man invites Arnold and Grandpa Phil to his house. He tells Arnold that he wishes Arnold was the son he never had, but he really does have a son, but they share nothing in common.