Megan Sullivan is H.I.V. positive, pregnant and missing. Initially the team suspects that her husband, who seemed to be less than thrilled about the baby, is involved, but soon learn that Megan had received a call from a prison, and their search tracks them to a former lover, who gave her H.I.V., her husband's former mistress, who had seen her taking part in a tense conversation not long before she vanished, and her own H.I.V. specialist, who had recently given her bad news. Martin thanks Danny for his help, and tells him that he is continuing to seek counseling for his addiction.
A reality show where a group of contestants are stranded in a remote location with little more than the clothes on their back. The lone survivor of this contest takes home a million dollars.
While Mac is busy working on her first State of the Union address, Rod becomes a tad tipsy and is found in compromising position with an intern for all the world to see. Meanwhile, Templeton sets out to find a way to sabotage Mac's Homeless Initiative Bill. Plus, Dickie and Jayne, who has gone back to being Templeton's chief-of-staff, go out on a dinner date.
It's congratulations all round for Matt and Joly as they celebrate their engagement. Rees is delighted, at last he's going to have a proper family, while his sister Yasmin has ex boyfriend Cash on her mind. Should she rekindle their passionate but dangerous relationship? Meanwhile Woody is in a panic - certain the police are on to him for Seb's murder. He is not the only one getting worried - Cash receives an unexpected visit from DI Davenport with a search warrant. Is the net closing in? Who is this woman Alison and child Rory that Matt slips away to secretly visit? Why is Alison so upset when Matt wants to tell Joly "the truth"? The kitchen's steaming with Rees' desire for waitress Lizzy. He can't wait to get her into bed but she's playing hard to get. He attempts seduction in the store cupboard but is left with egg on his face when Canteen almost goes up in flames. Bruno is convinced that Matt is after Joly's money - but how can he prove it? He suggests a quiet drink with reluctant Matt to find out more. As the two men psyche each other out - Bruno smells a rat and decides to find out more - engaging the service of a private detective. Meanwhile, Joly makes a sly trip of her own to visit Matt's mum in the nursing home in an attempt to make sense of the secrets that surround him. What she discovers turns her world upside down. Will she go ahead with the marriage plans? Cash turns up at Canteen - he wants Yasmin to bring their relationship out in the open but first he has to win over Joly, who is still furious with him for locking Rees in the deep freeze. Charming Cash has a way with words and soon even Joly is giving him the second chance Yasmin thinks he deserves.
A teenaged girl is found dead in her school with her wrists slashed, while a man has been tied to a tree and shot dead in the woods nearby. Stone and Alembic lead separate investigations, but is there a connection?
Lucas attempts to play in the first game after Keith's death, but cannot bring himself to do it; Nathan and Haley prepare to renew their vows, while Mouth tries to get closer to Rachel; Peyton receives a surprising offer; and Brooke finds a way to get revenge on Rachel.
The BAU team travels to Mexico to aid in the capture of a serial killer who is targeting elderly women.
Rose is surprisingly and vehemently opposed to Bernard's plan to create an S.O.S. signal; romantic sparks are rekindled between Jack and Kate when they trek into the jungle to propose a "trade" with "The Others"; and Locke begins to question his faith in the island.
With Kyle left behind, Cartman makes his way to FOX to get the Family Guy episode pulled, hoping to ultimately get rid of the show once and for all.
"Season Finale"- Everything hangs in the balance for the entire Lopez family: Ernie tells George that the factory is moving to Mexico and they'll both be out of jobs; the police want to question Benny for her part in an old robbery, so she flees; Angie has been feeling sick for days and awaits the results of a home pregnancy test; Carmen is afraid to open her final college letter after being rejected by her first three choices; Max has swiped a forbidden beer and is about to sample his first alcohol; and Vic prepares to propose marriage to younger woman he barely knows.
His search for information about his mysterious savior leads to an invitation for Haseo to join Ovan's guild.
Matthew Newton makes his debut in a green velvet jackets. As does Shaun Micallef in an enthusiastic t-shirt. Fifi Box returns all primped and put together like a proper lady. While Angus Sampson walks through the door in a tweed and leather jacket.
For the quickfire challenge the contestants are put under some serious money restraints. They have to choose from ingredients that are put in front of them that are priced by the pound and can only spend up to three dollars, but all the food on the Top Chef pantry was free.
A man dressed in a superhero costume is found dead in an alley, after saving a man being mugged. Mac, Stella, and Dr. Hawkes find his clothes in a nearby phone booth. Danny and Lindsay investigate the murder of an NFL first-round draft pick, known as "Superman."
J.D.'s brother Dan returns for a surprise visit and Elliot learns that J.D. has been telling Dan that she still likes him. A patient with weight-related problems needs an MRI, but he's too big for the machine. Carla and Turk freak out when they begin to discuss baby names. Meanwhile, Dr. Kelso assigns Dr. Cox to assist Ted with malpractice claim paperwork after Dr. Cox insults Dr. Kelso's son.
Veronica begins having dreams involving the dead students from the bus crash, who drop clues along the way. Meanwhile, Logan and Wallace become unlikely lab partners in Mr. Wu's class, and Keith helps Clemmons expose a doctor's scam.
Unhappy because Rory hasn't really forgiven him, Logan takes off with his friends. Rory runs into Luke and April at a bookstore in Philadelphia.
When a six-year-old boy is brought in with the same symptoms as another patient who died years ago under House's care, House believes the cases are identical and he can predict the course of the boy's illness. Meanwhile, the clinic hosts a poker night to benefit the oncology department.