Catwoman's cat, Isis, steals a cursed gem that causes Ace to run into a string of bad luck.
Jim, certain he will win the annual hot dog eating contest, is humiliated when instead he loses to a petit woman (Suzy Nakamura), and his problems are further compounded when Andy decides to date the female champion.
Streaky programs Dogbot to help Krypto so he can have more time with Kevin.
Rose tries to help the brothers sort out their feelings, when Charlie and Alan take their personal frustrations out on each other.
Curtis brings in a suspect who has critical information about Marwan's next strike. Michelle orders Curtis to use harsh methods to interrogate the suspect, but things get complicated when Marwan sends a lawyer to defend his rights. Logan's advisors begin to worry as he continues to exhibit fear in the face of the ongoing terrorist threat.
After Amy spends an hour chatting with Ray while he is trying to watch the basketball game, he tells Robert that she talks to much, which of course, Robert repeats to Amy, leading to a confrontation between Ray and "Lady Chatterly."
On the morning of his Julliard audition in New York, Ephram makes plans to meet up with Madison (guest star Sarah Lancaster) for coffee where he finds out that she was pregnant with his child. This devastating revelation causes Ephram to make decisions that will alter the course of his life. Amy tries to figure out what this will do to her and Emphram's relationship. Meanwhile, Dr. Abbott counsels a man (guest star Chris Penn) whose son may die as a result of a hunting accident.
Horatio's life is changed forever when he learns important information about his deceased brother. Horatio must now figure out what to do with this information about his brother, Raymond, and whether or not to tell Yelina. Meanwhile, the team investigates when a woman is murdered at a crowded bar after she's approached by a female employee of a service that helps men pick-up women. Also, when Delko loses his badge after some reckless behavior and it's used in a crime, he must locate the badge before it's used again.
The boys get out of jail only to find that Cory and Trevor messed up again and they don't own the park after all. Ray is hooked on VLTs.
Dana is stunned when Alice requests a bold sexual favor from her. Burr Connor (guest star Tony Goldwyn) reveals a secret to Jenny. Jenny learns about Carmen's real feelings for Shane, Kit plans a romantic night for Benjamin, and Bette and Tina have an intimate encounter as they bond over their unborn baby.
The school dance committee implements an experimental personality-based partner selection process. So, Chase tries to get matched up with Zoey, and so he does whatever it takes to get matched up with her. But of course, his plan backfires when another guy gets matched up with her as well as him. Zoey must pick between Chase and Glen, the other guy. Chase is upset and tries to get Zoey to pick him.
Dale dons a disguise to defy Arlen's smoking ban, and Peggy sets out to uncover his identity.
On this episode, Bam, his family, and friends go to Mexico. Brandon and Vito stay behind to learn and teach spanish. If Vito learns ten spanish sentences when they all come back, Vito gets to keep Bam's hummer.
The last surviving member of 'N Sync, Joey Fatone, must avenge his murdered bandmates in a deadly martial arts tournament in "Enter the Fat One". Check out a little scrambled porn on your 1980s-era cable box. M. Night Shyamalan has endless fake-outs in store for viewers in "The Twist."
Wyatt has taken Serena out on a few dates now, but their ""relationship"" is yet to be defined, and Wyatt finally gets up the courage to ask her if she'd like to be his girlfriend. Serena tells Wyatt she thinks she's a little too ""mature"" for him, being one year older and all, and Wyatt is crushed until Jonsey convinces Serena that younger guys are puppies – ""easily trainable"". Wyatt takes Serena on what Caitlin assures him is a ""mature"" date, but it ends up backfiring on him big time. Meanwhile, Caitlin's dream of being part of the Albatross and Finch family looks like it just might come true. The usually ‘legacies only' stores is holding an open audition for new Greeter Gods and goddesses and Caitlin has got her snobby stares to perfection. But her dreams of getting out of them lemon for good are shattered when the A&F crew choose Jonsey instead. Caitlin learns through Jonsey's experience that working at A&F isn't all the catalogues crack it up to be…
Jack runs into a bounty hunter named Joe who used to work at the FBI until his daughter died. He blames Jack for his daughter's problems. Although the team searches for Fantasia (a new designer drug) Levi learns that he will grace the box of the latest dog food only to learn that it isn't so easy to do. Sue and Lucy begin the have problems with the photographer that has chosen to photograph Levi. Sue and Lucy learn that Levi will have to compete with the photographer's dog in order to be included in the latest dog calendar.
Three old men from Yorkshire who have never grown up face the trials of their fellow town citizens and everyday life and stay young by reminiscing about the days of their youth and attempting feats not common to the elderly.
In an attempt to lure the sisters out of the manor, Zankou sends his underlings to attack Leo, in order for him to search the house for the Nexus and release the Shadow, the ultimate power. Meanwhile, in order to protect his parents Wyatt magically shrinks them and traps them inside a dollhouse, and Phoebe is left in charge of the newspaper.
Lynette learns that no good deed goes unpunished when she momentarily befriends the mean Mrs. McClusky. Susan's mother decides to try and jump start her and her daughter's love lives. Andrew talks to a priest about his feelings, and tells him of his shocking plans for his mother, Bree. Gabrielle has her credit card declined in an upscale restaurant, and Carlos sends Gabrielle a big message about what will happen if she leaves him.