Ephram prepares to leave for Europe as he feels that he has nothing left for him in Everwood. However, he's caught off-guard and questions his plans when Andy reveals the secret that Amy has been keeping from Ephram. Meanwhile, Nina and Jake contemplate going into business together, but the stress on their relationship proves a big obstacle to overcome. Meanwhile, Bright finally confesses he has feelings for Hannah.
Some new evidence comes to light in an old case that involves Dr. Macy. Jordan is placed in charge of the case that will either make or break Dr. Macy. Meanwhile, Woody is hot on the trail of a cop killer, and Woody finds himself looking down the barrel of a gun.
Bill finds happiness in a men's chorus, where the required devotion jeopardizes his Army career.
Sue and the team investigate a bank robbery but this bank robbery becomes a little more interesting than the team expected. They find out that the bank they are investigating was robbed several years earlier. This time they learn that three girls have robbed the bank, which begins to seem strange to the team. When they robbed the bank they stole shoulder pads and one of the girls is the daughter of the president of the bank that was being robbed. Lucy has a mystery of for a long to figure out after her grandmother gives her a jewelry box. When the team opens the box to find out what it contains they are all very surprised at what falls out of the box. Lucy learns that the letters her grandmother kept were from her first love named Oscar. Sue and Lucy decide to track down Oscar because he still wants to see Lucy's grandmother. Lucy is shocked when her grandmother learns of her surprise.
The contestants gather for one last time as the jury casts their votes for they believe should win the competition.
Flanders rents a room to two college girls who, without his knowledge, use the spare room to broadcast live softcore pornographic web videos of themselves.
Bart gets expelled from school and transfers to a Catholic school, where a hip priest named Father Sean tries to convert Bart and Homer to Catholicism, which worries Marge when she believes that Catholics do not go to the same heaven as Protestants and discovers that Catholic women do not use birth control.
Susan and Mike decide to move in together, much to Edie's displeasure. Meanwhile, Lynette takes steps to make sure Annabel doesn't come between her and Tom. Also, Bree comes to a realization about her "buddy" George the pharmacist who continues to interfere in her and Rex's lives. Carlos' legal problems take a turn for the worse, when Gabrielle decides to leave him. Mrs. Huber's journal reveals some secrets. Lastly, two new faces arrive on Wisteria Lane.
Unbeknownst to Lois, the boys enter her in the Mrs. Tri-County Pageant as a joke. When they overhear the other contestants remarking that Lois doesn't have a chance of winning, they plot to help their mother take the crown. Meanwhile, Malcolm is blackmailed into delivering love notes to a contestant for Herkabe, and Reese discovers that, according to the Mrs. Tri-County Pageant manual's scientific formula, he is beautiful.
After Mort bowls a perfect game, and Quagmire gets a key to the city by performing CPR, Peter notices he has nothing to be proud of. He then attempts to achieve fame by setting the world's record for most nickels swallowed. However, a slight miscalculation leaves him blind with nickel poisoning.
Jarry worries that Bullock and George Hearst will side with Montana on the annexation issue and a showdown looms between Wu and Lee. Andy Cramed holds his first religious service, though he doesn't count on Tolliver's participation.
Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother; Zoey, a pregnant woman in her 40s who's been diagnosed with cancer, disagrees with Cristina's medical advice; and the interns are mystified by Cable, a patient who's being treated for seizures and who thinks he's psychic.
Jonsey's new gig as the production assistant for local cable access isn't moving his new ""film career"" forward as quickly as possible, so he decides to film his own, ""Prank T.V."". And the first victim - Nikki. Caitlin agrees to be an accomplice and convinces her to spend the day with her getting a girlie make-over. Nikki reluctantly agrees and endures her personal nightmare of a day - manicures, waxing, and the ultimate horror - bikini shopping - all to make Caitlin feel better about getting dumped by a guy she wasn't even dating. But what will Nikki do to them when she finds out she's been pranked?
Three old men from Yorkshire who have never grown up face the trials of their fellow town citizens and everyday life and stay young by reminiscing about the days of their youth and attempting feats not common to the elderly.
"The World's Most One-Sided Fistfights" get wild at Mardi Gras. Benjamin Franklin grapples with historical figures like the Wright brothers and Mahatma Gandhi in "Educational Wrestling Federation." Oprah Winfrey fulfills all her viewers' fondest wishes...almost. A man in a public restroom encounters the terror known as "Dumplestiltskin." "12 Angry Little People" deliberate a crime most heinous.
Bubbles pretends to be a spaceman when the boys buy a rocket set. Ray reveals Lahey's secret and Lahey goes off the deep end.
A surprise guest shows up at a sad event as Bette gets stunning news about her job. Tina goes into a surprisingly difficult labor, Jenny finally reaches breaking point over her painful childhood memory, Alice struggles with her jealousy, and Peggy Peabody lays down the laws with her daughter, Helena.
When the body of a man is found and it soon becomes obvious the body has been moved, Eames and Goren investigate the death of Walter Czabo, whose wife has been sleeping with a decorated former police officer who happens to have close ties to Deakins. The suspects start piling up, starting with Frank Adair and leading to his controlling publicist, but Deakins is reluctant to go after his friend, who wields a lot of local influence, without good, hard proof.
When Stan forgets his anniversary, he arranges to have 20 hours of Francine's memory erased, but the CIA temp on duty accidentally erases 20 years. Francine, having reverted to her wild child days, moves into her old apartment with Hayley as a roommate, and ends up going to a festival with Hayley's boyfriend. Meanwhile, Steve asks a good-looking girl out, but needs his wingman, Roger, to "jump on a grenade" for him and date her ugly cousin.
When a person who was killed right in front of Phoebe comes back from the dead to blame her, she becomes guilt-ridden and vulnerable, creating an opportunity for Zankou to steal the Book of Shadows. Meanwhile, Paige has a new charge who knows nothing about magic, and Piper and Leo attempt to plan Chris's first birthday party.