A rebellious 16-year-old teenager is raped and murdered; the case becomes complex when they learn that her stepfather is a judge with whom she has had major problems.
The son of a medical doctor has set up what may turn out to be a dubious medical practice of his own, traveling with his brother from town to town and exploiting people...and finds that his past catches up with him.
After a near-fatal incident with Logan, Max decides to end their relationship for good. A murder committed by Alec's Manticore twin, Ben, puts him under suspicion and places all of the transgenics in jeopardy...thanks to White and his leakage to the media. Meanwhile, Joshua finds the perfect woman, but can't find the courage to confess his secret.
Joey prepares for an interview with Soap Opera Digest, although he's afraid of saying something stupid and getting himself into trouble, so he enlists his friends to make sure things go well. During the interview, he reminisces about his past acting experiences, his friends and his romantic life.
Tribal loyalties shift, Rotu's self-proclaimed leader is targeted for ouster and the sixth person is evicted.
Jack takes a vacation and uses the time to fulfill his dream of writing a novel. But when he gets frustrated, he pays an English professor to write the book for him. Meanwhile, Maya, Elliott and Nina are left to oversee the magazine and can't agree on even the smallest decisions.
D'Argo and Rygel meet Braca and Scorpius in a cafe to conduct negotiations when it is unexpectedly attacked.
Jane Galloway lives in fear. Her doors are triple-locked. Every shade is drawn. The bathroom window is nailed shut. An alarm system is activated. Who killed Jane, and how could the murderer have possibly entered, and left, the house?
Sylvia and Mark managed to save Buki's life after the tunnel collapse. Roisin told Cassie that she had withdrawn the statement and so was staying at Larkhall. Rhiannon asked Buki to get her drugs but Buki was scared off by the Julies. Jim tried harder to split Karen and Mark up, this time by banning them acting like a couple at work. Roisin asked Buki for ""something to help her sleep"". The Julies took painful revenge on Rhiannon's boyfriend/pimp by tipping boiling water all over him in the visiting room - they were put on report and were devastated to discover that they would have been released in a few days because without Virginia, the case against them collapsed!
As Dr. Greene's brain tumor begins affecting his coordination, he becomes concerned that his fate will be similar to the terminally ill patients he treats.
Hoynes and Bartlet each make an unexpected announcement about Hoynes' place on the ticket; fears of a terrorist attack arise when a truck carrying depleted uranium-fuel rods is involved in a head-on collision in an Idaho tunnel; Donna seeks a Presidential Proclamation to honor her high-school teacher/mentor who's retiring; and Bartlet's insistence on helping Charlie with his tax return sparks a discussion on the true nature of a tax rebate.
Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.
A stock analyst's murder leads the detectives to a corporation whose stock had fallen ... and plenty of suspects in the investors.
Ed's fast-talking big brother blows into town and ropes Ed into a risky plan to glam up Stuckeybowl; Nancy's Internet chat buddy turns out to be a little younger, but a lot older-acting than she expected; and Warren finally sees Diane in a new light after he fails to make headway with a college girl.
After hearing Bernie use inappropriate language at home, Bryana goes to school and repeats it—much to the horror of her teacher. Soon after, a social worker shows up at the house to discuss Bernie's hostility problems.
The boys have to sit through "The Russell Crowe Show" in order to see the premiere of the trailer for the new Terrance and Phillip movie. Meanwhile, Chef’s new TV has taken on a life of its own.
Charlie asks Joey to sing with his band at a distant club, which requires Pacey to give them a ride. Pacey and Charlie hate each other, and it takes a patient Audrey to keep them from going at each other's throats. Joey is nervous and isn't well received by the audience, until Charlie helps her with a duet. Still, he doesn't give up putting his moves on her. Audrey and Pacey, on the other hand, seem to be more and more in synchrony. Meanwhile, Dawson, Jen, Jack and Grams drive up to Capeside for Lily's 1st birthday, and Dawson finds out his mother has a significant other. Meanwhile, Jen confesses to Jack that she wants to break up with Dawson, while he is conflicted with the possibility of loving Joey again.
Musician Ricky Mathis becomes an overnight sensation thanks to his song "Rock Legend." When his music causes his fans to become obsessive and destructive, Sam, Alex, and Clover are called in to investigate the cause of this fanatical behavior under the guise of a supporting band. While Clover is enchanted by Ricky's music, Sam and Alex investigate the recording studio and discover they are using special glowing CDs that brainwash listeners. They must stop manager Sebastian Saga from using Ricky's music to take over the world. In the subplot, Clover has a crush on schoolmate Damon Reynolds, who plays guitar and hangs out with school diva and rival Mandy.
Ben decides that he wants to play an active role in his child's life. Lauren is pleased; but has already made arrangements to move to Arizona to be near her parents. Ben talks to Professor Hodges about the possibility of transferring to the University of Arizona. Adam's design wins the contest, and Felicity accepts an offer to stay in New York and help with his project. Hodges tells Ben that the deadline for admission has passed, but his friend can pull some strings and get him accepted. He must make his final decision in the next day. Felicity is upset that Ben failed to tell her about his possible move. She tells Adam that she may have to turn down the job. Trevor convinces Ben that Noel is still trying to make a move on Felicity. A tearful Felicity confides in Noel about Ben's situation. Ben catches them in an embrace and becomes angry. He says that he wouldn't have slept with Lauren if Felicity hadn't cheated on him. They break up, and Felicity accepts the job with Adam