A flashback offers a glimpse into the distant past of Vash the Stampede, his brother, Millions Knives, and the enigmatic Rem Saverem.
Weasel comes to investigate the world's largest hole, same hole I.R. tries to fill with cement.
Ben is surprised to get a letter from boyhood friend Lance Garcy. Turns out it's a chain letter, and Ben is quite awed by its power of causing tragedy to strike those who ignore it.
Kyle tries to manipulate Taylor into revealing the truth about her scheme involving Christine. Although Michael warns her to keep quiet, Taylor comes clean after Kyle threatens to break up with her. Kyle insults Taylor and her unborn child, then departs for the Dominican Republic. Amanda and Kyle's divorce is finalized. She marries Rory, as Kyle arrives at the ceremony seconds too late. Taylor tries to commit suicide through carbon monoxide poisoning. Jennifer tells Billy that she has known about Sam's affair with Jeff for months. Jennifer reveals her affair with Billy to Jeff and convinces him to tell Samantha. A furious Sam attacks Jennifer, but Billy comes to Jen's defense. Sam moves out of the apartment. Megan takes a job waitressing at the jazz club after the medical practice lets her go. She learns that Michael cost Brett the Philadelphia job by telling Larner about her past profession. She holds this information over Michael's head to stop him from making trouble at the practice
When Quinn and Colin finally access the coordinates to their home, the Sliders expect it to be their last slide. Instead, they arrive inside a security compound on a barren world, where humans and Kromaggs are fighting for survival.
When Daria agrees to help Trent find a birthday present for Jane, they somehow end up at a piercing parlor offering a two-for-one special. Hmm.
Alvarez knows who raped Glynn's daughter, but refuses to tell the warden. Wangler is making progress at school, but his cellmate, Adebisi, isn't a fan of higher education. When Augustus Hill's judge is convicted of accepting bribes, Said takes up Hill's case to get him a second trial. Diagnosed with cancer, O'Reily goes to a hospital to get a prison-paid lumpectomy, which is cheaper than a mastectomy. The Aryans are losing credibility in Oz, so Schillinger arranges to have a tough named Vogel killed with Beecher being the next on the hit list. Finally, the prison is filled with excitement as a woman, Shirley Bellinger, arrives on death row to be executed.
The son of a world famous mystery writer, Jimmy Kudo, has achieved his own notoriety by assisting the local police as a student detective. He has always been able to solve the most difficult of criminal cases using his wits and power of reason.
Ne'eg dies from being exposed to a devastating virus that was unleashed from an alien probe. The virus falls into the hands of a group of white supremacists, they release the virus into the Lincoln Hills homeless shelter. The deadly virus quickly spreads, threatening to decimate both the human and Taelon races. Boone, infected with the virus, comes up with an idea to develop anti-bodies against the virus but it may not be in time to prevent the virus spreading over earth.
Section falls into a trap when a mission to take out a Red Cell munitions base causes a virus to be spread throughout Section.
Charlotte is dating Jack, who wants a threesome, but she is unsure. Carrie discovers that Mr. Big has an ex-wife, and feels threatened. Samantha is seeing a married man; when his wife finds out, she proposes a threesome to keep their marriage together. Miranda feels unattractive and looks for affirmation that she isn't.
Old feelings reawaken in all the Gibsons, exacerbated when Laura is offered a tempting job by her old firm.
Arliss Michaels is the head of a sports agency and will do anything for his very famous clients.
Lisa inadvertently gives birth to a junior genie in a misconceived attempt to teach Chett a lesson about responsibility.
Lisa's efforts to "erase the hate" among students at Farber High result in aliens invading Earth.
Carly, a 14 year old girl breaks into The Hive and for some reason Ros is put in charge of her, which she is not too happy about. Beckett is moving into a rather run-down flat which Alex found for him, and his friendship with Ros is rather ‘rocky'. Carly is taken off Ros' hands by a man who turns out to be a baddie after an ancient funeral mask that the Bureau are looking after. He manages to con Carly into stealing the mask and once she realises why they want it, she runs off and hides it. Soon, both Ros and Carly are held prisoner until Carly gives the whereabouts of the mask. They are trapped under a lift. Carly manages to get out and tell Alex and Ed where it is hidden, and they quickly find it.