In hopes of raising his little sister Delia's spirits, Ephram does his best to recreate his mother's Thanksgiving traditions as the Brown family spends their first holiday without her. Meanwhile, in order to save a patient's life, Dr. Brown must find the man's missing brother, who is believed to live in the woods; and curmudgeonly Dr. Abbott attempts to befriend the entire town when he has a health scare and questions whether anyone would attend his funeral.
Horatio, Speedle and Calleigh root through the evidence in the homocide of a strange, and unorthodox college professor when they find him tied to a tree. Elsewhere, Delko and Megan investigate a car found in the water with a dead body in the trunk, and immediately suspect an insurance scam.
Tyr receives a communication from a human on an abandoned planet and leaves to meet her. As he does, a mad scientist boards the Andromeda using dark matter ninjas. After beating them, the man introduces himself. He loves the woman Tyr is with and wants to kill her, if he cant have her, nobody can. After saving her, he forgives her and lets her live. The episode ends with Tyr revealing that she is actually a Neitzian, the last female from Codiac, Tyrs pride. He says that he wants them to start a new Codiac pride but she refuses and Tyr leaves.
In the midst of a career crisis and much to Annie's dismay, Eric takes a job as a talk DJ at a college radio station, but things become serious fast when Eric and his producer find themselves counseling a male student who calls in threatening suicide during his first shift. Lucy refuses to spend time with Roxanne which puts Kevin in an impossible situation. Later on, Roxanne asks her boss to assign her a new partner as tensions simmer between her and Lucy. Ben is almost arrested when he accompanies Simon and Cecilia to an underage club. Ruthie tries to figure out a way to breakup with her boyfriend without making him cry.
Alan makes a new friend at the BP garage called Dan. They both drink Director's bitter, use Lynx deodorant and both drive Lexi (the plural of Lexus). Dan asks Alan to present a prize at the Norfolk Bravery Awards, where Sonja is hopeful of the opportunity to try out some of her practical jokes.
When the Read family car breaks down, Arthur is heartbroken. He wants to save the vehicle before his parents replace it.
Doug loans Carrie to Deacon to help prepare Thanksgiving dinner. When Deacon ditches her for Holly's services, his web of lies soon gets out of control. Trying to cover it up, Doug continues to dig a hole for himself.
While Raymond, Robert, and Frank don't want to bring up the fact that Marie is having vision trouble, Debra decides to level with her and suggests she visit an eye doctor. When Marie gets a pair of glasses just in time for the holidays, she winds up spotting and pointing out everyone's physical insecurities.
After a sitdown with Carmine and Johnny Sack, Tony contemplates the future of the HUD partnership. Meanwhile, Paulie blows off steam with an old pal; Janice starts losing patience with the obsessive Bobby; and Melfi ponders the Freudian undercurrents of Tony's latest dreams.
Thinking Homer does not find her attractive anymore, Marge decides to get liposuction, but instead receives breast implants. She becomes adored by many of the men in Springfield, and becomes a spokesmodel for trade shows. Meanwhile, Bart and Milhouse try to imitate a stunt they saw on an episode of Batman that guest stars Krusty the Clown. When the stunt ends badly, media watchdog groups blame Krusty, forcing the clown to make his show more safety-conscious and less fun.
Dr. John Becker goes through his daily routine of being a doctor, stopping at his favorite diner, and other various situations, all the while hating life and everything around him.
Dimitrius gets a less than pleasant surprise when a man he had thrown in prison twelve years ago begins to spy on him and his family. Meanwhile, Lucy battles with a doctor who claims that her car dented the passenger door on his car.
Acting dumb like Reese eases Malcolm's stress and lands him a date with the new light of his life, an attractive girl who's really a dim bulb.
Cupid's on the hunt in the Degrassi halls. While one character acts on her crush, another keeps hers anonymous. The question is: will either girl get the guy she wants?
Hank is opposed to Bobby's taking Home Economics, until his domestic skills outshine those of Peggy, who tries to sabotage his Thanksgiving meal.
Mike searches for a link between a dead farm worker and a spate of animal deaths. Alfred leaves David high and dry in Whitby. Meanwhile Tricia is upset, because of her patient dieing. She soon starts to feel guilty over the death of Len. She thought that it was tetanus but lad results come back with poison and she blames herself for not picking up on it. Even though there was nothing she could have done she still blames herself and feels that she was bad doctor.
Yuri Andreyevich Zhivago is a young doctor and rising poet, about to be married to Anna. He meets Larissa Ameliava 'Lara' Antipova (the teenage mistress of a politician) when she tries to kill herself. Lara marries the Bolshevik Antipov, and as the Great War unfolds, Yuri and Lara go off to war to tend the wounded, fall in love and lead a passionate affair as the old régime collapses.
Clone High refuses to let women or animals play basketball, so Joan devises a plan to become a member of the team, turning Abe "Weakest" Lincoln into a jealous wreck.