Following a stunning betrayal to their team, Brian and the FBI race to stop an NZT-enabled Sands and his associates from orchestrating an international incident. Also, Brian experiences devastating side effects when his NZT immunity starts to wear off.
When Jimmy has trouble admitting that he's 51, he throws himself a second 50th birthday party. The party triggers flashbacks of where he was a year ago, showing Jimmy what a difference his family has made in his life.
Yolanda takes her friends to task for questioning her health issues; wounds are reopened when Kyle's sister, Kim Richards, returns to talk about her difficult year; Eileen confronts Lisa Vanderpump, causing her to break down in tears.
Jake Anderson tries a dangerous short cut with only one working engine on the boat. Casey and Josh perform surgery at sea. Edgar Hansen captains the ship while his son Eric works as greenhorn. Captain Keith turns his life around.
The murder investigation of a suburban mom takes a turn when her child is abducted.
A teen patient with abdominal pain firmly refuses any drugs. Meanwhile, Dr. Halstead reconnects with his past when treating a patient; a pregnant woman does everything in her power not to deliver the child; and Dr. Rhodes tries to avoid family issues.
Lex finds out that a woman who had close contact with an infected patient has disappeared.
Harry loses his cool with 3 swimmers that he's forced to rescue just seconds after warning them not to swim in a dangerous area. However, calling them "imbeciles" and "idiots" puts him in hot water.
A possible sighting of Genghis Khan's lost tomb dead patches in the desert and the world's oldest and strangest lakes.
Jenna tries to decide between success at Idea Bin and her tenuous friendship with Matty. Jake has an unexpected hookup, and Sadie and Sergio find themselves baring more than ever before.
The S.H.I.E.L.D. team is left reeling and decimated as Hive continues to sway Inhumans to his side. But there is a sliver of hope as Agents Fitz and Simmons follow a lead that may be able to stop the maniacal Inhuman once and for all.
When a Chinese pop diva is killed, her female bodyguard is blamed for the murder, who appears to have been passed out at the time of the homicide.
After being emasculated in front of Cece, Schmidt insists on a manly bachelor party weekend in Vegas, but the road trip goes awry when the guys end up at a desert biker bar and he must put his newfound bravado to the test.
Alison brokers a peace with Paul in time for the gastropub opening, but Joe goes missing.
When Kenny decides to audition for the school play, “Zombie Romeo and Juliet,” Eileen volunteers to help out. Kenny receives the role of Romeo, but much to his dismay, his ex-girlfriend Mimi is playing Juliet. Things get more awkward when Eileen, realizing that this may be the only time she will see Kenny marry a girl, begins to treat the play’s wedding scene like an actual wedding. Meanwhile, Pat and Jimmy both struggle to talk to their new crushes.
Deborah's sister Viv comes to visit, stirring up the family, especially Deborah's suspicions that Maurice might be gay. Deborah needs to take action, but struggles to find the best course. Meanwhile Amy has a secret she wants to tell Maurice, but will he be able to return her honesty?
The artists work in pairs to execute large-scale back pieces testing texture...and each other’s nerves.
When Mindy needs to get her financial affairs in order, she turns to Jeremy's ex for assistance.
The upper class area of Arcadia, CA promises solid auctions for the buyers. Darrell and Brandon come out swinging, but get caught trying to pull some shenanigans. Rene brings his father Gunter to help hunt for collectibles and Ivy takes a gamble for something out of the ordinary.