After a dead body is found near a 300 year old finger bone, Booth and Brennan investigate the site, which might be hiding pirate treasure.
Libby lends a helping hand to Hurley to support him when he begins to think the island is having a strange effect on him. Hurley begins to see Dave guest-star Evan Handler, Sex and the City on the island, who was his friend in the mental institution Hurley was in. Also, Locke's sense of purpose is shaken when the prisoner gives him new information about the hatch.
Cartman and Kyle are at war over the popular cartoon, Family Guy. Kyle loves it and Cartman hates it. When the show airs some controversial content the boys go on a cross country chase with the fate of Family Guy lying with the first boy to reach Hollywood.
Jonas and the team carry out an assasination of a terrorist in Spain. However, they soon find out that the government called off the mission and will now not protect them in the country which means there only hope is to escape. Back at the base, Molly learns that her daughter Betsy wants to drop out of college and Kim thinks about taking a college course herself.
Melinda, a troubled teenage girl who is immuno-compromised as a result of the medications she must take after a heart transplant, has a severe allergic reaction and goes into shock when her boyfriend visits her. Meanwhile, House and Wilson continue to work out the problems in their new living arrangement.
Rory forgives Logan, then needs some time for herself, so she pays a visit to Lorelai in Stars Hollow. Although Lorelai refuses to admit that she is upset, Rory can tell that she is bothered by the news that Luke will be gone for a few days on a field trip with his daughter, April. And, against Lorelai's wishes, Rory pays a visit to the store owned by April's mother, Ana, to spy on her. Meanwhile, when Zack finally works up the courage to ask Mrs. Kim for permission to marry Lane, he is surprised at the deal she makes with him.
Gibbs and the team are called in when a couple of kids stumble upon the body of a missing Marine in a frozen lake. As the NCIS team searches the frozen lake bed for clues, they come across three more bullet-ridden bodies. During the autopsies, Ducky and Gibbs discover that the three additional victims had gang tattoos. With this crucial piece of information, the team works to uncover the Marine's connection with a deadly street gang.
When J.D. rearranges his schedule to allow himself more time with Turk, Turk secretly resents hanging out with J.D. because it interferes with his own "Turk Time." Meanwhile, Cox and Jordan go on a double date with Elliot and Keith, and Carla covers for Kelso at work as he grieves for his dead dog. Later, a patient almost dies after giving up part of his liver for his brother, and the hospital staff learns about making sacrifices for the people they really care about.
An improvisational comedy series in which a celebrity performer is dressed up in costume before passing through a door into a room where they are welcomed with the phrase "Thank God you're here."
A serial paedophile murders members of a family and kidnaps the two younger children.
With the help of a time machine built Dzherry, spies are in the future, where the world is ruled by Mendi. Mendi nail breaks in training. David invited her to participate in a TV show, and she agrees.
A televised poker cash game in which top pros including Sam Farha, Doyle Brunson, and Johnny Chan compete. This is not a tournament however, each player is playing with their own money and they have the option to buy in again.
Terrence other villains organized community that was named L.U.ZH.A. Clover and Mendi can not decide - whose place the photo on the cover of the magazine. Both girls went out beautifully, so their images are combined into a single photo.
Jack and Wayne locate a source inside Logan's administration who has information on Palmer's assassination. But things get complicated when they learn that Henderson is using leverage to keep her silent. Audrey is forced to choose between Chloe and Buchanan as Homeland Security begins to absorb CTU.
Flashbacks shed light on the past actions that led to the incarceration of Lincoln, Sucre, T-Bag and C-Note. Basis of Michael's ingenious break-out plan are revealed. Dr. Tancredi memorizes how she ended up in Fox River State Penitentiary.
After dates, Christine faces a critical moment in her relationship with Burton. Will she or won't she Let him in the house, that is, to meet her son, Ritchie. She eventually relents, only to be thrown for a loop later.
Although Jake is back from rehab and going to 12-step meetings every night, Nina realizes she has no idea how to deal with his recovery. Andy cancels his first Internet date to give Nina emotional support. Amy tries to impress Professor Fields by using her father, which results in Dr. Abbott lying to his daughter about his past. Ephram encourages Kyle to meet with his long-absent father, opening old wounds for Ephram regarding his own son. When Delia asks Andy to listen to the rough draft of her Bat Mitzvah speech, he is deeply touched by her memories and her message.