The whole hospital finds out about Stewart and Crystal's relationship, much to Lydia's dismay. So to prove to them she is moving on with her life, she throws a party. However, things don't turn out quite like she planned them.
While the riot intensifies, Abruzzi and Sucre join forces. Michael must decide whether or not to save the life of Dr. Tancredi.
Ted agrees to let Barney spice up his love life, and ends up on a crazy adventure of flying to Philadelphia, encountering the law and visiting the Liberty Bell.
Nancy gets busted and Heylia teaches her about a $14,000 lesson. Doug and Celia make kitchen talk. The kids have daddy problems during diversity week. Bread-sticks and Scones, Nancy's bakery, opens and doesn't start off so well. And Celia retakes the PTA by way of a technicality.
Allison dreams that she's a woman who's been committed to a mental institution in 1959. After viewing taped sessions from the clinic, Allison discovers that the woman from her dream had made claims of being Allison DuBois, living in 2005.
The search of a missing 17-year-old girl, whose trip to Miami turns into an ongoing nightmare.
Jack's old mentor, Gerard, comes to Nolita with a strange request. He wants Jack's food to feed him to death. Meanwhile, Steven and Seth's authority drives Jim to find his way up the kitchen hierarchy with ineffective results.
Mona decides to embrace her birthday for a change and throw a party honoring Dee Dee and her. However, the event is spoiled by Phylllis's gift to Mona: a certificate to have her eggs frozen at a fertility clinic. Meanwhile, Dee Dee receives a great job offer with a law firm, but decides to pass because her instincts tell her something else will come along. Her friendship with an NBA star soon leads to a new opportunity for a career.
A sportscaster becomes a full-time dad when his ex-wife decides to accept a job out of the country and his teenage daughter, Breanna, moves in with him.
Todd takes action when Toni has difficulty handling her motherly duties. Meanwhile, Joan becomes fed up with her friends' freeloading at the J-Spot.
Paige has her entire future planned out; she is going to the best university in Canada, Banting, and she will live with Matt and everything will be perfect. That is until Matt comes back changed. Soon things go from bad to worse when Alex convinces her to get stoned with her. Meanwhile Jimmy is proud to be the new basketball coach but a new member, Derek., poses trouble.
Cross Over Episode with Las Vegas. When a pair of bodies ends up in the Boston Morgue, one clue will lead to fabulous Las Vegas. With Woody in Vegas and Jordan and Boston temperatures rise on a couple of…couples.
Lilly re-opens the case of young girl, an overweight college freshman named Laurie, who died in a fraternity house fire in 2004. The fire was deemed accidental at the time, but a cell phone photo e-mailed from the girl's phone just moments before her death prompts a closer examination.
Whitman has gotten on the wrong side of Chrissy after catching him in the female changing room. At the monthly M&M meeting, Hurley places Rob in a position to speak out against Whitman in front of the entire department.
Calvin continues to spend time with his other family, and the barbershop suffers in his absence. Isaac steals a famous client from Yinka, and the two barbers eventually come to blows. A ventroliquist and his dummy cause trouble for Jen and Dana at the bed and breakfast. Yinka falls in love with a married Nigerian woman (Nzinga Blake). Romadal is arrested for assault.
When Stan's father passes away, Stan reveals his real father is actually Jack Smith, a super suave spy. Jack convinces Stan to quit the CIA and work with him at the Scarlet Alliance, an ultra-secret spy group. Francine is upset with Stan, who is busy training with Jack for a mission involving uranium, artwork and terrorists. But when the FBI shows up at the Smiths' house looking for an international jewel thief, Francine suspects Jack is the fake.
The series focuses on an eccentric motley crew that is the Smith family and their three housemates: Father, husband, and breadwinner Stan Smith; his better half housewife, Francine Smith; their college-aged daughter, Hayley Smith; and their high-school-aged son, Steve Smith. Outside of the Smith family, there are three additional main characters, including Hayley's boyfriend turned husband, Jeff Fischer; the family's man-in-a-goldfish-body pet, Klaus; and most notably the family's zany alien, Roger, who is "full of masquerades, brazenness, and shocking antics."
A budding romance between Casey and Sam seems to have little chance of growing after Derek informs Sam of the “male code,” which prevents friends from dating their best friend's siblings. Elsewhere, Nora and George take a quiz to determine how well they know their kids.