Sam investigates a case about missing babies whose parents are being murdered. At one of the crime scenes, he discovers a baby that was left behind and calls Dean for help. Reluctant to leave Lisa and Ben, Dean finally agrees to meet Sam and surprises his brother with how parental he has become. The brothers take the baby to Samuel, who decides to raise it as a hunter, which infuriates Dean. However, before they can decide the baby's future, a shape-shifter breaks in and attempts to kidnap the baby.
Jack and Dan go off on their own, yet again, after they are assigned to help a forensic specialist with a burglary case. Weary of the specialist's superiority complex, the duo breaks free only to be tangled up in another case entirely. They must get help from an unlikely source to save Liz when she gets in trouble working a high-profile prostitution sting.
When Linda is asked to do a Lindana reunion concert, Lawrence worries that she might be missing the excitement of her old life, so he asks the boys to help turn him into a pop star so that he can perform at the concert and show mom he too is an exciting guy. Across town, Dr. Doofenshmirtz plans a faux alien invasion in order to take over the Tri-State area.
When a young woman appears to be strangled while participating in a live online chat that Adam witnesses, the CSIs must determine if it was real or a hoax, and locate where the possible victim is.
A good Samaritan with a police record takes action against a terrorizing subway criminal, forcing the Reagans to weigh the rights and wrongs of vigilantism.
While watching a news broadcast, Alex discovers that Mason (in wolf form) is in the Poconos Mountains trapped by country wizards. The country wizards will only give back Mason if Alex trades them their portal. Alex then discovers that the country wizards have turned Mason into a half wolf form. But can she live to be with Mason like this without being embarrassed by him?
The boys get a chance to see one of their hometown friends when she comes over to visit, who happens to be very clumsy. Meanwhile, James gets a visit of his own by a crazed fan.
Audrey and Nathan investigate when a gust of wind seemingly throws a woman into a wall following an argument, and the FBI agent suspects some children may have telekinetic powers.
Rex encounters a group of Evos, and discovers a link to his past. He goes undercover to take down the leader of the group, and learns more about his past, and how it could affect his current life.
In an attempt to fight the titan, General Steel and his men seek out an extra terrestrial weapon. Meanwhile, Lance and Ilana discover the importance of teamwork.
A recent rape is linked to two similar attacks at a chocolate factory 10 years previously, leaving the team no choice but to reopen all three cases. The detectives uncover news of an unhappy workforce, learning of an alleged suicide, and their investigation becomes even more complicated when they discover a severed finger was found in one of the company's snacks. After a visit to the doctor, Gerry decides to quit smoking, and instead of resorting to nicotine patches or gum, he enlists Sandra to help him quit
Ash and Iris try to help the owners of a Hot Sand Resort who are being plagued by Sandile.
This week's case hits close to home for DS Matt Devlin when investigating the death of a police officer, and his best friend, PS Pete Garvey. Devlin and Garvey had known each other since childhood and when Matt discovers Pete had recently been in contact with their childhood parish priest Jonathan Nugent (Matthew Marsh), his suspicions are alerted as Pete claimed to have been sexually abused by him as a child. With nothing but suspicions and unfounded rumours to go on, a murder charge cannot be brought against Nugent. Now a married man with a family of his own, can Matt really be sure they've got the right man? James and Alesha take an unusual approach in order to bring a charge - any charge - against the accused in a desperate attempt to get the case home.
The team investigates when a woman is attacked by a shark in the pool at a Las Vegas casino.
Liz uses her newfound confidence to solve Pete's problem with a difficult editor (Paul Giamatti); Jack tries to cheat mortality; Tracy vows to be present when his wife gives birth.
Tired of scrubbing toilets, Fin applies for a job at Captain Ron's. Reef finds out and tries everything to destroy Fin's chances at getting the job.
Performance is low and the boss tells Tod that somebody has to be fired, and it appears that Manmeet is the one who will get the ax, although Gupta is convinced that he will be the one.
Stefan takes drastic measures to find out the real reason Katherine has returned to Mystic Falls, and is shocked when she reveals new secrets about what really happened in 1864. Damon tries a new tactic to resolve his issues with Mason,.... but it proves costly. Tyler pushes Mason to tell him the truth about the Lockwoods. Finally, when Katherine delivers an ultimatum, Stefan and Elena are left with very few options.