After the Chief announces his retirement, rumors begin to circulate on his departure and successor. Mark is determined to leave Seattle for good but Meredith accidentally has him stay after letting him know of the open Chief position. Derek is angry at Meredith for causing Mark to stay in Seattle, but soon realizes that she is not the reason he is really angry. The attending physicians at Seattle Grace Hospital fight to get Richard's attention, but he expresses his disappointment. He also displays his lack of support in Bailey's plan to create a free medical clinic, but she ultimately goes through with her plan when Izzie offers to spend her entire 8.7 million dollar inheritance on the project. George, devastated after his father's death, uses sex to overcome his grief, and eventually proposes to Callie. Cristina and Burke still don't speak to each other, but he breaks the agreement when he proposes to her. Richard endeavors to reunite with his wife, Adele, and decides to retire, only to come home and find his wife with another man.
At Keppler's request Catherine uses a different approach to catch the killer, and in doing so she deceives the rest of the CSI team. The team soon discovers that something is amiss in Catherine’s investigation.
Tony's a smart kid. So smart he believes that he can get his best mate Sid laid... and make a profit.
Clark is in his barn one moment... and the next finds himself in a psychiatric hospital where he discovers he's been suffering from delusions that he came from another planet and has super-powers.
In Memphis, a truck fire brings Sgt. William Ashton and the homicide team to the scene of a double murder. When the smoke clears, Ashton must track down a series of suspects in pursuit of the killer. In Kansas City, Kansas, Det. Bill Michael works the murder of a woman found dead in the street. With few leads to go on, he's wondering how to find the killer when anyone could be a suspect.
The Winchesters investigate a series of crimes where robbers with no criminal past commit suicide after the hold-ups.
After Ash suffered a defeat last time, he doesn't let it bother him as he trains with his Pokémon for his rematch with Roark. Meanwhile, Team Rocket resurrects an Aerodactyl that goes nuts and nearly destroys the city. Can Ash be able to face this ancient Pokémon again? And will Dawn be ready for her next contest?
On Mt. Shumi’s snowy peak, Afro faces the vicious two-sword technique of Kuma, a bizarre enemy keenly aware of the horrors of Afro’s past.
Sandy, Ryan and Seth prepare for Kirsten's upcoming 40th birthday party, however Kirsten learns some news that will change her life forever. Kaitlin tries to stop her mother having a secret love affair. Taylor visits a therapist and Ryan pretends that he doesnt miss her. Elsewhere Che finally learns that Seth isn't his soulmate.
The five remaining teams take a surprise trip to San Diego's Mission Beach, where the beauties must learn about radio waves and electronics while the geeks must put together their own fitness routines. One team is eliminated at the end of the episode.
Andy, Ryan and Jim are stunned when they find out that Dana and Cheryl recently appeared in a Chicks Gone Wild video.
Allison dreams about a strange friendship between two recently murdered ghosts. When she tries to help one of the ghosts solve his murder, she is surprised when he declines her help.
Just as Carmen prepares to go off to college and George and Angie begins looking forward to being empty nesters, Angie discovers that the Lopez family could be growing. Meanwhile, George's job is in jeopardy, Benny faces jail time for a crime from days gone by and Vic contemplates engagement to a much younger woman, in the season premiere broadcast.
Can knowing a secret be a motive for murder? The CSI team must figure out if a change in gender is cause for the death of a showgirl. Also Lindsay goes back to Montana to try to put the person who committed the murder of four friends behind bars.
The Panthers have only one more game to win in order to qualify for the play-offs. Smash's mother discovers something that could end his football dreams.
Haley finds herself frustrated over her injuries while Skills and Mouth help Nathan find a job as a stripper in order to earn money for the senior prom. Meanwhile, Brooke betrays Rachel in order to get with a new guy and Lucas and Peyton finally reach happiness in their relationship.
Veronica and Mac help campus researchers locate a missing monkey who was allegedly stolen by animal rights activists. Meanwhile, Keith is approached by Mindy O'Dell, who claims her husband's death was murder, not suicide. And in the aftermath of his breakup with Veronica, Logan turns to Dick for advice.
Monica manages to seduce Frank and sink her claws back in, but he dare not tell Sheila that he and Monica have been sleeping together. Sheila proves to be a frightening adversary when scorned and Frank could be in real danger. But neither Sheila nor Monica want to share him and he has to decide on which wife he wants. But who will he choose?