After stowing away aboard the flight containing Henderson's contact and the incriminating recording, Jack finds himself having to deal with a pilot who refuses to cooperate. Martha begins to break down, and Mike becomes suspicious of what she is hiding from him, while Logan tries to calm his financial backers.
Lily, Barney and Robin attend a high school prom to scout out a potential band for Lily and Marshall's wedding reception. In order to get in Lily and Robin pretend to be the dates of two kids who were going alone. Ted and Marshall are back at the apartment where they are preparing the invitations to be sent out.
Allison repeatedly dreams about a woman who is being watched by a stranger in her bedroom.
Westmoreland wants Michael to speed up the planned escape, and gets Bellick one step closer to unraveling it. Michael has to decide whether to involve Sara in the breakout plan. Tweener's devotion is put to a test. Veronica finds out that her ally unexpectedly has a connection to an inmate serving time at Fox River.
Jakes teacher has a meeting with Alan and Judith to discuss the lack of interest Jake has at school. Alan starts to fall for Francine, in a platonic way, because he is tired of the lack of intelligent communication he has with Kandi. Charlie helps Jake audition for his school musical.
Christine tries not to have a meltdown when her ex-husband, Richard, brings his new Christine with him to pick up Ritchie and take him to breakfast so that they can get to know one another. By day's end, Christine tries to pull herself together to make a good impression at parents' night at Ritchie's school, but is caught off guard when new Christine shows up as well.
Doug and Deacon discover they have more in common with each other's wives than their own, so they start hanging out with each other's wives as well.
Isis gets her hands on the Pied Piper's flutes and takes control not only of Metropolis' rats, but of Krypto and Bat Hound too.
When Hank rejects Bobby's request for expensive designer jeans, Bobby takes his dad's advice and gets himself a really "cool" job; but begging on the street isn't exactly what Hank had in mind.
Parenting expert Jo Frost goes around America helping parents deal with their children's behavior.
Brian's gay cousin Jasper comes to town to marry his fiancé, until Mayor West bans gay marriage to distract everyone from a financial scandal.
Piper and Phoebe devise a plan to recover Leo. Meanwhile, Paige rescues her new charge from a Darklighter Billie is forced to make an important decision.
Gabrielle and Carlos are shocked when the father of their baby shows up to take the baby back. Cops and a lawyer arrive to a house on Wisteria Lane. Lynette tries to help Ed heat up his sex life. Meanwhile, Karl decides to break up with Edie, as Edie has no idea that Susan is the other woman. Edie causes a fight to break out in a bar, after she trips a waitress. Lastly, Bree is taken a step forward to help Peter when she finds out how bad his other addiction is.
The family attends "Stab-A-Lot: The Itchy and Scratchy Musical." The musical's director is a graduate of Springfield Elementary and Principal Skinner puts his foot in mouth when he makes sexist comments about her education and that of women in general. He tries to make the situation better, but only buries himself deeper and deeper until he is fired and replaced by Women's Educational Expert Melanie Upfoot. The first thing she does is split the school into girls and the boys. Lisa dislikes the way girls are being taught math and she ventures over to the boy's side of the school in search of a challenge. Disguising herself as Jake Boyman she starts attending the boy's school but while she finds the math problems more interesting, it is being a boy that is a greater challenge.
David and Carlos are still investigating the poison that is affecting Charringa's lemon crops in Florida, before the United States decide to bomb Cuba. Jill, on the other hand, asks Mayko to contact all the other labs using the same stem cells from Korea to let them know a retrovirus is in that strain. Bob offers to verify all the steps one more time with her and see if her findings are correct. Simon Jessup finding that Glenn responds to all the stimuli suggests that he undergoes brain surgery.
Huff gets an unexpected visit from his father. Teddy ends up meeting a very attractive young lady while down at the beach. Izzy finds herself arrested on a DUI charge. Beth decides that she will host a meeting of Paula's prayer group. Russell tracks down his young client, who is at a drug house, and then ends up joining in the festivities.
Vito considers starting a new life in New Hampshire, while Anthony continues his pursuit of revenge against Junior.
Addison's patient is a Catholic mother of seven. Addison gets in trouble after learning that the patient's husband won't use contraceptives. Derek treats a divorce attorney who asks if Derek is in need of her services. While Izzie and George are talking about their personal lives they "overhear" part of Derek's conversation with the divorce attorney who calls herself one of Seattle's best. Alex gets in trouble with Addison yet again for not being able to keep his mouth shut when other people think he should. A legendary jazz musician refuses to see medical reason. The musician is Burke's musical hero. Finn makes Meredith breakfast.