The romance between Inspector Murdoch and Dr. Ogden heats up as Murdoch finds himself investigating the death of a young woman working as a high-class prostitute.
Paddy wakes up to find himself chained to a bed in a strange room, unable to remember how he got there, and tension arises between Frank and Monica following a DSS investigation. Carl schemes to discover Micky's sexuality, Tom's last-ditch romantic gesture to regain Debbie's affection backfires, and Carrie decides it is time for a change
Sam, Ben and Sock encounter a few surprises on their return from a road trip; Andi refuses to speak to Sam; the Devil has a new assignment.
As Christian and Liz make their wedding plans, he also looks for a new cancer treatment. Meanwhile, Ram Peters drops Kimber for a newer model, while Teddy informs Sean that someone close to her is gone, and Sean and Christian repair a couples neck wounds which look strikingly similar at McNamara/Troy.
LuAnn's housekeeper returns after a monthlong trip to the Philippines---to the relief of LuAnn, who had been saddled with the extra house chores. In other developments, Jill organizes a charity event; Simon and Alex enjoy a spa day; Kelly participates in an elite Hamptons horse show; and Ramona's husband organizes a tennis doubles rematch with Jill---resulting in a volley of egos.
When a teenager is murdered, the alleged killer's defence barrister has an audacious plan up her sleeve.
The squad tracks down a serial killer who has been mutilating women; Ham is temporarily partnered with Butch during Bobby's absence; Earl tries to persuade Grace to help Leon.
After receiving a tip from "Rebel", Matt and Peter race to Building 26 to rescue Daphne and recover files that will expose the government's plans for those with abilities. Claire finds help from an unlikely source in smuggling Alex out of the city. As Sylar and Luke continue their road trip, Sylar begins to have memories of his father that lead him to the truth about his mother. Meanwhile, "The Hunter" puts his own agenda into action with an explosive surprise for one of our heroes.
Charlie battles father and son villains with the power to stop time. Meanwhile, his poor school grades and academic probation threaten his ability to play basketball.
What Jessi and Kyle find in Cassidy's safe sends them searching for the truth about Sarah Emerson, but Jessi's unrelenting method may endanger her life. At home, Declan finally puts his foot down, and Josh already misses Andy.
Allison is asked to help find a missing daughter and her visions seem to incriminate her father, but Allison believes this is wrong after a chat with the woman's mother. Meanwhile, Joe is suffering from sleep deprivation, while Scanlon and Lynn's relationship is severely tested.
When pirates take over a luxury yacht, Delko's future as a CSI is threatened just as his relationship with Calleigh moves to the next level.
Charlie has to remove a half-naked woman from his bedroom before Chelsea arrives.
Juma and his men take the White House by storm, killing most of the Secret Service and trapping Taylor and Jack in the saferoom. His efforts to extract her are thwarted until he is informed that the President's daughter is in the White House as well. Renee and Larry try to convince Vice President Hayworth to let them rescue the President, but Hayworth will not budge until the FBI can produce proof that she is not in imminent danger.
Not even at the halfway point of this hellacious day, two planes have collided outside of D.C., there has been an attempt on a chemical plant in Ohio, the President’s husband’s life has been threatened and the nation remains at risk. When Dubaku’s evil plan escalates to his boss, General Juma (guest star Tony Todd), the stakes are raised and steadfast President Taylor faces a deepening foreign policy dilemma.
Chuck gets jealous when Sarah has to seduce a Fulcrum agent. Meanwhile, Jeff and Lester start looking for the "Buy More Babe" as a way of finding a new employee.
The gang thinks that Barney must have a secret girlfriend after noticing his bizarre behavior.
A paintball game leads to a fight between Sheldon and Penny, and romance for Leslie and Wolowitz.
The contestants make over a group of female extreme fighters into their drag daughters. Xena herself, Lucy Lawless, makes a guest appearance to judge the girls' combat prowess.
Emma keeps a watchful eye on the citizens of Dog River to ensure the town reigns supreme over Wullerton ('spit') in "Turn Off Your TV Week". Lacey and Oscar find a profitable way to break the rules and Karen and Davis hit the radio airwaves to help everyone cope. Brent finds a creative way to get through a week of no TV with the help of Hank and Wanda.