A sportscaster must take on the responsibility of being a full-time dad when his teenage daughter moves in with him.
A bullet-riddled truck containing human bones is pulled from a river and it's believed that the remains are those of a 17-year-old girl who went missing in 1932. The investigation reveals that the girl was the sister of a bootlegger who happened to own the truck. It's also discovered that the white teen may have been in a relationship with a black girl who had another lover---the jealous type.
Homer sees a movie about the end of the world and fears the same thing will happen in real life after seeing a chain of random occurrences (celebrities ["stars"] falling from the sky, raining blood, a man in a realistic devil costume) and doing a complicated math equation that predicts the end will come on May 18th, but when the end does not come, Homer discovers a flaw in the equation and ends up in Heaven where he meets God and learns that God is planning The Rapture.
Bree begins to feel guilty about her friendship with George while Rex's health continues to depreciate. Lynette tries to spice things up with Tom who, she fears, is losing interest. Meanwhile, Mr. Shaw consults with Paul, and ends up lying to Susan. After talking with Kendra Susan learns what Mike did. Gabrielle tells John that she is pregnant, and John doesn't take the news well. Lastly, Felicia takes action to help Zach, and to get rid of Paul for good.
Lisa agrees to enter a Krusty-sponsored "Li'l Starmaker" competition and panics when another contestant (guest voice Fantasia Barrino) outperforms her.
Derek and Meredith try (unsuccessfully) to be discreet as they spend the night together at Meredith's house, but their haggard appearance speaks volumes to everyone - including Bailey, who warns Meredith to end the relationship. Meanwhile George suspects an anesthesiologist of drinking on the job but is reluctant to speak up about it, Alex treats a former competitor who now finds honor in self-mutilation, Izzie has to deal with a patient who won't let go of his girlfriend - literally, and Cristina seems to be battling a case of the flu.
Brian becomes a substitute teacher at Chris' school after his teacher wins the lottery. When Brian is moved to teach a class of troubled kids, Chris falls in love with his new teacher, Mrs. Lockhart, who promises to love Chris only if he kills her husband. When Lois finds out, she and Stewie decide to teach Chris a lesson.
When Hal decides to attend his first annual Neighborhood Association meeting with Malcolm, he is strongly encouraged to take on the role of President. Being his dad's right-hand man, Malcolm sees a perfect opportunity to add some excitement to the community, while Hal's agenda is a little bit different. Meanwhile, Francis takes on a new job as a camp activities coordinator and turns to Dewey for his input on some creative new games. While Dewey revels in his afternoon of fun, his fed-up classmates take their teacher, principal and janitor hostage.
Cochran's ominous prognosis puts the camp on alert. Smallpox survivor Andy Cramed returns as a minister. Swearengen asks an unlikely pair to pull a scam on Commissioner Jarry. Martha Bullock has second thoughts about staying in Deadwood.
Adam catches a glimpse of the wonders of travelling in the Tardis, as they head to a future, where Satellite broadcasts to the entire Earth Empire. But anyone promoted to Floor is never seen again, and the Doctor suspects mankind is being manipulated.
Sue Thomas is a deaf woman who works for the FBI in Washington, DC. Using her ability to read lips and assisted by her dog Levi, she solves tough crimes that her hearing colleagues and listening devices can't crack.
When a failed alchemical ritual leaves brothers Edward and Alphonse Elric with severely damaged bodies, they begin searching for the one thing that can save them: the fabled philosopher's stone.
The SAS is sent to Chechnya to find rebel leader Movzar Mazayev. Henno mistrusts Russian Special Forces agent Vasily who is assigned to help them. The soldiers close in on Movzar's fiery sister Sapiyat but intelligence officer Kathy is taken hostage. In this conflict where political ideals and personal tragedy overlap, can Red Troop bring down their targets and rescue Kathy?
Brash, stubborn and resourceful ME Jordan Cavanaugh revives her career in Boston, occasionally breaking the rules and ticking off the cops or her co-workers. On the home front, she gets crime-solving help from her retired-cop dad.
Batman is pitted against a new villain named Clayface, who can transform his body as if it were clay and impersonate anyone he chooses! Before The Batman can stop him, he will learn Clayface's shocking dark secret! Part 2 of 2
Since Wuya now works with Chase, Jack strikes back by forming an alliance with Cyclops. Jack uses the Sphere of Yun SGW to lock up Chase and take over his legion of jungle cats. Jack appears to be unstoppable. Omi is in the precarious position of having to help Chase in order to stop Jack.
Jack and Katnappe compete to become Chase Young's apprentice.When Katnappe wins, Jack is so disheartened that he considers giving up evil for good.Omi seizes the opportunity to turn Jack around and prove that he really was destined for good, only to have his optimism used against him.
A UFO is briefly seen flying through Los Angeles with no clear indication on what it is, but Agent Eppes discovers it was heading for the Staples Center and starts an investigation into the possibility of mass terrorism.