On House and Cuddy's flight from Singapore a passenger gets ill and Cuddy suspects an epidemic. At the hospital, Wilson leads the team as they deal with a middle-aged woman suffering from seizures.
Kavanaugh acquires what he needs in order to apprehend Vic who is preoccupied with getting revenge on Guardo. Claudette finds herself under the political microscope as a result of the San Marcos incident, and Danny receives some news about her future at the Barn.
McGee is under high pressure during the murder investigation of a Petty Officer based on the character for his latest book, with very little information to go on.
To find the remaining suitcase bombs, both Jack and the President set up bluffs.
Robin attends Lily's bridal shower and finds the gift that she brought is out of place. Barney hires a stripper for Marshall's bachelor party.
Wayne must deal with legal arcana in an eminent-domain case and Dahlia gets a job for which she is equally qualified: a dental hygienist. Ginny catches up to the Malloys, which means Dale is probably not far behind.
Ruby and Louise tries to learn the Hippity Hop Dance. Meanwhile, Roger teaches Max how to play football.
Carrie is convinced that Deacon and Kelly were only able to afford a vacation home by being cheap. Meanwhile, Arthur tries to help Spence get a new job.
Everyone gets in the action as Season 3 comes to an end on High Stakes Poker. Phil Ivey, David Benyamine, Antonio Esfandiari, Brad Booth, Patrik Antonius, Phil Laak, John D'Agostin, Brian Townsend, and Daniel Negreanu close out the season playing $300/$600 No-Limit Hold'em on High Stakes Poker.
Emerging as head of the 'hood, Tommy gets scammed while trying to evict drug dealers. Jimmy demands payment from Jenny; Nicky learns the Donnellys are behind Louie Downtown's disappearance.
Trying to send an e-mail to Barb about Mr. Harris, Christine ends up sending it to all the parents from school, nearly costing him his job.
Charlie takes a liking to Myra, the witty sister of Judith's fiancé, Herb.
Manny's parents want her to come home after the tragedy at Emma's house and to Emma's surprise, Manny agrees. She can't seem to tell Manny how she feels though, since Manny's got a spirit squad competition and a brand new boyfriend to balance. Emma can't hide the fact that she feels ignored and when she thinks her friend's death is being glossed over she decides she really doesn't have to hide her feelings. At all. Dylan has been absent, grumpy, and completely mute making Marco worry that Dylan is cheating again. Jimmy and Spinner are happy to help catch him in the act, but none of them are expecting what they find...
The future of the team is threatened and without having that to deal with, Sandra has to take drastic measures to prevent Jack from exacting revenge against the man who killed his wife Mary. Sandra also has the added benefit of trying to keep Jack’s actions from shady new recruit DCI Karen Hardwick while working on a 10-year-old murder case.
After a scalped body is found near a Native American casino, Horatio believes that the owners of the Casino and the County Supervisor may have had some involvement in the murder.
Five teenagers must locate and secure ancient relics with unbelievable power, while at the same time stop a demonic corporation who want the relics for their power.
Vince's new agent wants him to do a period film. In the meantime Eric and Vince agree to have lunch with Ari and Turtle plans Vince's birthday party.
After being divided into three teams of two, the final six candidates travel to Las Vegas to launch a promotional campaign for a Trump project.
Susan meets her in-laws and finds out some family. Victor is still taking his chances with Gabrielle, while she has a devastating catastrophe at her home. Lynette is encountering new problems at the pizzeria while an unexpected relationship develops on Wisteria Lane.