Peter travels to Primatech in Texas to destroy the virus, but not everything is what it seems. Hiro continues the pursuit of his father's killer, while Matt pursues the last Company member in the photo. Nikki is reunited with Micah but has bad news, while Maya has to choose to remain with Alejandro, or go with Sylar.
While the gang try on their Halloween costumes in the Finster's garage, they find TP+KF carved on the wall. Chuckie believes that Tommy has a crush on Kimi. The argument between Tommy and Chuckie escalates to where their friendship falls apart. So the rest of the gang tries to bring the two back together, but backfires. The two eventually make up when Chuckie saves Tommy from the middle school goons who were chasing him.
Eight Canadians with poor driving skills are sent to an army base. They undergo challenges to enhance their driving abilities. Weekly, the most improved driver leaves. The last remaining participant is deemed Canada's Worst Driver.
Lifestyles of the rich and famous come under the CSI microscope when a wealthy family's nanny turns up dead.
William considers leaving the firm as he feels disrespected at work. Maya starts to write a neighborhood newsletter as Joan feels Lynn doesn't like her housewarming gift.
Alan finds out that Charlie stole his girlfriend and works on a plan to get back at Charlie, even though this happened when they were in high school.
Riley joins Thugnificent's Lethal Injection crew. Meanwhile, a local bully steals Riley's prized chain.
When Barney loses his way with women, he hopes a trip to the Victoria's Secret Fall Fashion Show will help him regain his form.
Chuck discovers that his former roommate and old nemesis, Bryce Larkin, is still alive, and that a renegade group within the CIA is after the Intersect. Chuck then has to balance helping Bryce return to the legitimate CIA, with the year's busiest shopping day at the Buy More.
Hannah shares her feelings with Nick and decides to take her life in a new direction. Eddie is having problems showing his feelings for Janet in public. Nick learns that another professor has taken over his class. Physical Phil is on the verge of losing the only connection to the world outside of his house.
A mysterious stalker from Adam's past shows up on Wisteria Lane, and they have dinner. Detectives question Gabrielle about Victor's whereabouts. Danielle's baby puts stress on Bree and Orson's marriage. Lynette has a reunion with her long-lost stepfather, Glen. Susan notices Mike is behaving strangely.
Dexter realizes it won't be easy to end things completely with Lila. Dexter tries to stay ahead of the investigations as the manhunt for the Bay Harbor Butcher intensifies. An enemy of Dexter figures out his secret.
It's Thanksgiving and Rose is fed up with everyone. She leaves and they are forced to figure things out on their own. Freddy and Marty Trio use some information to get a holiday furlough from prison.
An unexpected visitor shakes miss Matty, but she keeps it to herself. The rumor that the railway will reach the town ruins the happy atmosphere. When Miss Deborah goes to talk to Captain Brown of this, he is of no help, indeed their friendship is severely strained.
Kitty and Robert takes dance lessons. Tommy gets a surprise visit and Kevin makes a drastic decision.
After Quahog is hit by a flood, Meg winds up in the hospital in a coma. When she wakes up and sees a cute med student, they immediately hit it off. Overprotective of his daughter, Peter is determined to drive the med student away. That is until Meg reveals that she is pregnant.
Bobby gets mixed up with racial intolerance at Tom Landry Junior High. Meanwhile, Lucky hurts himself by catching a frisbee made of barbed wire and the gang has to convince him to go to the hospital.