Brennan is about to go out for dinner with her old professor and ex-lover when Booth asks her and her team to help identify the remains of a young woman found in a refrigerator.
When a teenager and her younger sister end up in the hospital after a day at the park, detectives learn that both girls were abducted from New Orleans after Hurricane Katrina along with a third sister who is still missing. Despite the interference of a local reporter, Jackson Zane, detectives are able to catch the kidnapper, a known pedophile, and recover the girl, but when Alvin Dutch dies and the autopsy determines it was Anthrax, Benson puts everything on the line so that she can get the truth out there.
A drug lord is gunned in his Coconut Grove mansion and a suspect arrested at the scene claims he sells marijuana to Delko. Stetler, from Internal Affairs, investigates and the case quickly gets personal when Horatio gets involved. As for the shooting, the CSIs learn that two gunmen may have been involved. Also, Calleigh makes a major decision concerning her job.
After Dee Dee complains about Brett's sexist treatment of her, Charles and Spencer show up at the office to confront him. Their actions backfire, as everyone at the office begins thinking of Dee Dee as a "daddy's girl." Dee Dee, with encouragement from Mona, Phyllis and Big Dee Dee, sets out to prove herself by trying to land a successful athlete who has refused to sign with any agent.
A sportscaster becomes a full-time dad when his ex-wife decides to accept a job out of the country and his teenage daughter, Breanna, moves in with him.
When Joan decides to shut down the J-Spot, the restaurant starts bringing in money when William flips it into a sports bar.
The premiere of Jay and Silent Bob Go Canadian, Eh! is here, and Paige and Alex find out how fun hanging out can be. Meanwhile Emma, who is at the premiere with Peter secretively, discovers Snake and Mrs. H making out.
It's the Christmas season. Simon discovers that Rose (Sarah Thompson) may have secrets, and begins to wonder if his parents were correct when they warned him not to rush into marriage. Meanwhile, Kevin and Martin come to blows over Martin's attitude about becoming a father and Eric and Annie finally allow Ruthie to date Jack (guest star Garrett Strommen). Simon drops by to Glen Oak to talk to Eric and have...pie. Rose tells her dad about her being embarrassed about his numerous failed marriages as well as her mother's numerous relationships. That is the reason why she hasn't introduced her family to Simon yet. Philip encourages Rose to hold back on marriage with Simon and just live with him, while Rose debates that she tried that and the Camdens hate her even more.
Following Monica's sudden death, Danny becomes the main suspect. Danny and Casey arrives at the Montecito for a hostile takeover, but it appears that Monica's will leaves Montecito to a foundation for the blind. Mike is assaulted in the stairway after breaking up a fight, which leaves Danny, Ed and even Mary to find out whom could do something like that to Mike. Ed takes care of Monica's will, and her belongings.
After being forced into knocking back 5 shots, so he will stop thinking, Ted goes on a partying rampage. The next morning he wakes up with a woman in his bed, but he does not know who it is. So he turns to his friends to try and piece the night together and work out who the woman is in his bed.
Allison dreams about hitting a girl with her car and a woman who's house is haunted. She finds out that the woman killed herself. Now Allison is trying to put all the pieces together.
Lydia becomes jealous when the kids befriend Crystal, then makes them go with her to visit their former housekeeper.
Sheppard finds himself on a planet where time passes more rapidly, with no way to contact his team or return to Atlantis.
With Lincoln's execution scheduled for the following day, Veronica comes out of hiding to contact him and gains an ally. Kellerman makes the ultimate sacrifice to preserve the conspiracy. Michael looks for a way to get Lincoln out of solitary confinement in time for the escape that evening. The inmates risk everything as they attempt their escape.
Charlie helps Alan with his obsession of always having to get approval from the women in his life.
Doug and Ray Barone have a "guy's night out." Meanwhile, Carrie gets a shock upon visiting her mother's grave.
Brent feels that his rapidly thinning hair is the town joke, and seeks help from Lacey. True to her nature, Lacey only makes things worse for him. Wanda gets a lamp at an estate auction that causes strife at Corner Gas; Hank tries to fix appliances and Lacey's magic ways impress Oscar.
A copy cat killer starts to terrorize Boston, Woody and Jordan are left to break the case. When they have to turn to the original killer for answers, Jordan is less than comfortable when the killer starts to get personal.