Edward and Alphonse discover that the young boy on Yock Island is, all at once, an alchemist, a homunculus and able to transmute his own body.
Tensions still run high in the Yokas household; Lester preps Bosco for Mikey's hearing, and then pulls a switch when he cross-examines him on the stand, leading to Mikey's getting RORd; Sully realizes what a toll the job has taken on him by his reaction to the deaths of three people in a robbery at the restaurant where he eats breakfast every day; Faith and Bosco answer a call which leads them to Lester's house, where they find his daughter not breathing; Sully tracks down and arrests the restaurant murderer; after Dr. Hickman tells Faith and Bosco that Lester's wife and daughter have been severely beaten, Lester is arrested; Sully gets his LSAT results; Ty and Sasha get closer.
When trying to save a scientist from Dr. Drakken’s secret arctic base, Kim and Ron are hit with a truth ray which forces them to speak the absolute truth about every issue. Kim soon discovers that this is a huge embarrassment while Ron is enjoying his newfound truth potential, but can they get through the day without causing themselves huge problems?
Kim catches a nasty cold from the Tweebs, but still accepts a mission to guard a mysterious machine. After Drakken and Shego steal the device, her mother insists that she stay in bed to rest while Ron and then the Tweebs take up her duties. By the time matters are resolved, everybody on both sides of the conflict has caught the cold.
Claudia tries to alleviate Sean's hypertension and high blood pressure by running the household all by herself but everything goes awry. Jimmy gets suspended from school, which causes a set of problems all its own, and Lily and Brad break her bed so they steal the family car... and get it impounded.
After a series of humiliating run-ins with Dash, the school bully, Danny uses his powers to get revenge and triggers the ghost of Poindexter, a kid who was shoved in his locker so many times he haunts it to this day. Danny must battle this ghostly defender of nerds and geeks, while proving he's not the bully Poindexter thinks he is.
Carlos reports the locators on the two Terrorcons have concluded that the enemy has two bases (Megatron and Alpha Q), while Megatron's plan doesn't succeed as Team Rodimus comes to rescue Scorponok. After the report, Dr. Jones is unveiling a new starship to increase Energon production, named the Miranda II. Optimus reveals their mission is twofold: they are also going to destroy Unicron, and they prepare to set up a space bridge.
The owner of a gallery specialising in Islamic art is discovered in the boot of a submerged car. Armed with a clue found in the dead man's flat, Alembic and Stone head for a casino, but their investigation is destined to end in further tragedy.
An attorney in need of a heart transplant rues the day he checked into Kingdom Hospital. Meanwhile, Hook discovers authentic newspaper clippings inside Mary's doll that reveal the horrific details of the 1869 Gates Falls Mills fire that killed scores of children on the very ground where the hospital now stands.
Elliot asks Sean to move in with her, which only adds to J.D.'s problems. Turk is unsure why Dr. Miller's attitude towards him has changed, until he finds out that Carla un-invited her from their wedding. Dr. Kelso outrages Dr. Cox when he announces that Sacred Heart will begin doing full body scans, starting with an ever present hypochondriac patient, who wants any freebies he can get.
Pratt struggles to diagnose a woman who suffers mysterious chronic seizures. An attractive woman, Campbell, informally accuses flirtatious Pratt of sexual harassment. Abby ponders how to get her contentious patients' attention during her psychiatric department rotation.
The heroes get lost in a forest. Just then, May gets taken away by a Skarmory. As Ash, Brock and Max try to get May out of the forbidden area, May befriends a Bulbasaur, but the other Grass-type Pokémon start attacking her.
The crew ended up on Floridia 7 and in the middle of an election between Dark Clown Confederation presidential candidates.
When a male corpse with the same name as a female neighbor of Tru's comes into the morgue, Tru suspects identity theft. When the day restarts, Tru's investigation takes an unexpected turn that makes it difficult to sort out just who is the victim and who is the criminal. Meanwhile, Tru and Davis piece together some information about Jack, who hasn't been forthcoming about everything in his past.
After Rachel makes a startling announcement about her possibly accepting a new job offer in Paris, Ross secretly schemes to get her former job back at Ralph Lauren. Joey is so flustered by all of the upheaval in his friends' lives that Phoebe prevents him from learning about the sudden death of his agent Estelle. Meanwhile, Monica and Chandler check out the house for sale next door to their new suburban home and make a stunning discovery.
When Chloe accidentally inhales a mysterious krypto-gas, she discovers it acts as a truth serum to anyone who comes in contact with her and decides to take advantage of her new power by going to the Kents to find out Clark's secret. However, her new power comes with fatal consequences and Clark must find an antidote before she discovers the truth about him or worse, dies.
While dissension among Xindi ranks festers, Enterprise tries to recover from a devastating attack.
All the children of South Park are attracted to Mr. Jefferson, his son and their home filled with games, toys and animals. Cartman goes out of his way to get Mr. Jefferson to love him while the local police force resent him for being black and wealthy and decide bring him down.
G Wing say a final farewell to Yvonne while Jim gets another shock when Lauran turns up on his doorstep asking questions. Tanya makes Sylvia an offer she can't refuse & Neil gets offered a new job from an unexpected source. A full-scale investigation is launched into Yvonne's death, and while Jim finds it hard not to crack, Colin appears to be the prime suspect. The wing is shocked by Yvonne's death, but Julie J has a bigger shock in store. The new wing governor introduces herself to G Wing, giving the women yet another surprise. New inmate Darlene is quickly befriended by Phyl, who is interested in her drug stash.
As they kick off their season against a rival team from Stonewood, the local Dog River hockey team finds itself at a crossroads. Brent is a great goalie and is being taken for granted by his teammates, so when an offer from the rival team comes his way, he has to seriously consider his options. Meanwhile the other players are having trouble scoring and might need to take some advice from an unlikely hockey expert. Then team super-fan Emma learns the hard way that you should never mix cars, your husband and a hammer on game night.