Jack forces Nina to work with him to get the virus from Amador. Palmer meets with Sherry and convinces her to help him deal with Milliken. Chase remains in Mexico to help with the capture of the virus. Ramon and Hector quarrel when Hector wants to pull out of the deal.
Unable to handle the pressure from Dan, Nathan decides to quit the basketball team and looks to Haley to help him fill his free time. Meanwhile, Brooke becomes increasingly jealous of Lucas and Peyton's growing friendship.
Lorelai is upset that Luke has gotten an apartment in another town. Rory learns that a guy she likes has been spreading false information about her.
Nick finds out how hard it is to get the trust of the people he hurt back. Burton feels Nick isn't ready for a heavy caseload that might hurt Fallin & Fallin. Nick wonders if the bus driver caused the accident on purpose. Lulu tries to place Connor Adams in a foster home and understand why Nick had the affair with Suzanne.
Sharon faces pressure from the powers that be behind her talk show, who are disappointed in her performance and expect her to work harder. She refuses to incorporate their suggestions into the show. Kelly and Jack grow tired of appearing on Sharon's show; both refuse her request for a co-hosting appearance. Ozzy very reluctantly agrees to appear in the Halloween episode. He believes that he is going to just be a guest, and is furious when he learns (at the last minute) that he is to serve as co-host. Meanwhile, the Osbournes' property undergoes some re-decorating. The workmen struggle to move a gigantic Buddha statue across the yard.
The Korean shop-owner next to Flex's barbershop raises unexpected objections when his daughter begins a mini romance with Flex.
Rory steals a police dog when he hears about CJ's glory days of stealing his old school mascot, but Cate is shocked when the dog finds marijuana in Kerry's backpack. Meanwhile, Bridget gets brought home by the police for not wearing a helmet on her boyfriend's motorcycle after Cate telling her she has to.
Kev accidentally proposes to Veronica, and although he soon admits he's still legally married to Roxy, they decide to go ahead with a fake ceremony anyway in order to claim a small inheritance from Veronica's father.
Dana and Jim both covet their reverend - she for romance, he for the pastor's prowess at bowling.
There's a big gymnastics meet at Degrassi, and Manny's going to lead the team to gold! But when she starts to feel sick, she fears that her queasy stomach might be more than the flu or even a case of bad nerves. And she's suddenly not sure she and Craig used protection when they had sex. Not knowing where to turn (it's sure not going to be her strict mom), Manny turns to Emma's mom Spike, the one person she knows who's been in her shoes. When Manny's worst fears are realized, she finds support from Spike, Emma and even Craig, who takes the news surprisingly well. Toby's feeling more and more shut out of JT's new world of hanging with the cool kids, especially when Jimmy invites JT to DJ Mad Bullets concert. So Toby comes up with a plan to win Jimmy over: he'll hack into the school's computer system and alter Jimmy's math grade. After all, if there's one thing a nerd like Toby knows, it's computers! So what can go wrong?
On a temporary leave from military duty in Iraq, Martin's father pays the Camdens a visit to help his son decide whether to forgo college for a career in professional baseball. However, the visit turns sour when Martin catches his father kissing Roxanne. Meanwhile, Chandler and Paris reevaluate their relationship in the wake of her ex-husband's return, and Roxanne comes to blows with Martin's aunt over their differing views on the war in Iraq. Lastly, Vic tries to join the Marines and talks to a supervisor over the matter.
Paris and Nicole get a job working with a taxidermist; Paris is homesick and relies on Nicole to cheer her up.
Sin City screeches to a halt as a massive power outage brings down the light of the strip, locking down the Montecito, while a mysterious hotel guest is shot on the casino floor. In the midst of the blackout, super sleuths Nessa and Delinda attempt to find the casino killer, while a semi-delirious Sam flirts with paranoia as she suspects the murder to be part of an elaborate cover-up. Elsewhere, a trapped Danny and Mary spend the blackout rehashing some old feelings, while a claustrophobic Mike works tirelessly to free Ed and himself from the lockdown surveillance room.
Dr. Brown tries to intervene when a bulimic high school champion wrestler (guest star Douglas Smith, Gregory Smith's brother) puts his life in jeopardy for an important tournament. Bright is suspended from school after he fights with Amy's boyfriend Tommy (Paul Wasilewski). Linda Abbott suspects that that Andy is reluctant to move their relationship to a more intimate level because of her HIV status. Finally, Ephram is convinced that college student Madison is embarrassed to be seen with him.
Experiment #608 - Slugger After Pleakley's incompetence in baseball causes Lilo, Stitch, and Stitch's cousins to lose to Mertle's team, Lilo and Mertle arrange a rematch, with Lilo's collection of Elvis records and Mertle's collection of dolls on the line. Lilo finds Experiment #608, aka 'Slugger', and decides his projectile-deflection skills would make him an excellent pinch-hitter for her team. Unfortunately, Mertle gets her own ringer in Gantu, and makes the rematch a game of basketball instead of baseball, with Slugger on the line as well! Can Lilo and the experiments win under these circumstances, or will they need help from an unlikely source?
Brennan and the Mutant X team join forces with a time traveling mutant to diffuse a bomb threatening devastating consequences.
When Wanda quits her job after getting passed up for a promotion, she tries to re-channel her energies toward Bernie. The togetherness starts to wear thin, however, when she upsets Bernie's writing process as he prepares for his talk show appearance on "The Ellen DeGeneres Show." Meanwhile, Jordan wants to become friends with the big boys on the block, and figures the best way to do it is to hook one of them up with his older sister, Vanessa.
Jamie Cruickshank, a bartender at the Maid in Splendour public house, is keen on Bella Monday, a barmaid, and follows her to a tumbledown old cottage in the woods, only to be blasted with a twelve-bore shotgun. Then the pub landlord's son, Stephen Bannerman, is also killed in the same way. Barnaby finds there was ill-feeling between locals and newcomers to the village and also between the landlord and his aggressive son, who was in the process of taking over the business.
Carrie gets upset at Aleksandr for being inconsiderate of her feelings about Samantha's cancer. When her new family outgrows her apartment, Miranda considers buying a house in Brooklyn. Charlotte receives a dog and names her Elizabeth Taylor. Samantha's hair falls out as a result of chemotherapy.