When a doctor comes to New York to search for the missing daughter of her drug-addicted sister, Faith and Bosco focus their attention on the child's stepfather, a New Jersey cop, after they discover that the girl was taken by a man in uniform; Tatiana returns home; Jimmy spends some quality time with Joey. The crossover starts on ER S08E19 Brothers and Sisters
While drawing up their will, Greg and Kim have a difference of opinion on who should get custody of Sam in the event of their deaths. Kim wants Jimmy and Christine to have him. Though Greg thinks Jimmy is too irresponsible, he ends up deferring to Kim's wishes. When they tell Jimmy and Christine about it, Jimmy wonders how they expect a mooch to raise three kids. He learns that Greg's life insurance policy will handle that. But since Greg only agreed to trust him with his son and not his money, the funds were entrusted to Greg's sister instead. Jimmy is insulted that Greg feels he's too incompetent to manage his finances. Against Greg's wishes, Kim decides to give Jimmy $1500 of their tax refund to invest to prove his mettle. After a failed attempt at playing the stock market, Jimmy takes the entire $1500, plunks it down on a wet suit and scuba diving lessons, and starts up a golf ball retrieval service, fetching balls that golfers hit into the lake then selling them for profit. Greg b
Event: AN-NAJAF, PERSIA 422 A.D. Mac Hollingsworth, an old-school relic hunter, leaves a key to Pandora's Box to Sydney in his will. She and Nigel travel to Baraq, where they are befriended by a local conman and petty crook, Ahmid. With Ahmid's help, they get into the palace where Pandora's Box is secreted...disguised as harem dancers. The palace is controlled by Colonel Montoya and his henchman Hauer. Sydney finds the hidden door the key opens, but she and Nigel are captured. Montoya opens the Box and is incinerated. As eclipses and earthquakes plague the land, Hauer forces Sydney and Nigel to decipher a clue to re-seal the Box. They do so, then manage to stop Hauer from selling the Box.
J Street has become an Atavus hybrid, Renee rushes to locate an antidote.
Eric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
Justin's making too much money as a go-go dancer to care about his suffering schoolwork. George offers to take Emmett on a world tour! Detective Carl Horvath returns to the diner, to ask Debbie out on a date.
An embattled psychiatrist probes the boys' naughty behavior patterns in a session framed by flashbacks to past episodes.
When a wealthy publisher is murdered to prevent him from exposing an elaborate confidence game that enveloped him, his company and one of his editors, Goren and Eames run their own con to extract a confession from the killer.
When the murder of a city auditor and his family seems too perfect, Goren and Eames turn their attention towards law enforcement personnel after learning that the auditor was investigating a number of former cops upon suspicion of double-dipping.
Percy takes off his glasses to make himself look young again; Olie and Pollie get roles in a school play; a robot helps Olie and his family clean up a mess.
Doggett catches someone in the X-files office trying to steal documents pertaining to Mulder's sister. The intruder is a severely scarred man who blames his disfigurement on Government conspirators. He claims the source of that information - and, in fact, the one who helped him gain entry - is Mulder. Although he refuses to divulge the missing agent's whereabouts, the mystery man has enough knowledge of the X-files and its history to lead Doggett to suspect that he just might be Mulder himself. Scully's fears for the safety of her son are elevated when he is injected with an unknown substance. With the mystery surrounding William becoming even darker, Scully must allow herself to send him away for his own safety.
Hank learns that the incident estranging Dale from his cowboy father was a cover to keep him in the dark about Dad being in the closet.
Zorak has set up a booth were children give him money to beat them up. Unfortunately, the business has been taken over by Butch.
The League aid the Justice Guild against their arch-nemeses while trying to unravel the secrets of the Guild's world.
Inspired by a cartoonist who speaks at the school as part of a career day assembly, Bart creates a comic book series based on Homer and his anger problems, which turns into a popular Internet cartoon series called Angry Dad. Homer finds out about this and is at first outraged, but after talking to his family, he decides to try to become a less angry person.
Ruth continues to help an injured Nikolai recover, but her patience is tested when she discovers just how he broke his legs. Brenda's escapades help her to write, but her feelings about being engaged grow more muddled--especially after Billy's release from the hospital.
A new student, Laticia Bowers, comes to Lucky Junior High. Her quirky behavior and the fact that she's a mortician's daughter makes her an outcast and target of gossip with the rest of the students. When Ginger and her pals accept her as a friend, will they get Courtney and the "dominant social group" to go to a party at her funeral home house? Meanwhile, Carl and Hoodsey go to Brandon's birthday party.
Soames continues to try and track down where, and with whom, Irene is. Winifred gets the surprise of her life when her husband returns out of the blue. Holly and Val announce they are married and will be moving to South Africa. Soames married Annette and finally he gets a child, but he also loses someone close to him.