15 year old Amy ends up pregnant after one night at band camp, throwing her whole life upside down. It doesn't help that she's now going to school with that guy.
An apple-tree cake for a local orchard inspires Buddy to try a new recipe. Meanwhile, Mary doesn't think Buddy's giving her 40th birthday cake enough attention, so she threatens to go to another baker.
Leonard is aghast to find out a secret of Penny's: she believes in psychics. Meanwhile, Sheldon tries to assist Koothrappali in picking up a girl at a university mixer.
When Barney debates giving up wearing suits in order to land a hot bartender, his conflicted feelings lead to an amazingly awesome musical number. Meanwhile, Ted gets one step closer to meeting the future mother of his kids.
Three incoming freshman attending college football powerhouse Blue Mountain State University must quickly adapt to college life while juggling football, girls and nonstop hazing.
When Castle and Beckett are called to a wedding to investigate the death of a bridesmaid, Castle is stunned to discover that the soon-to-be bride is his old flame, Kyra, "the one that got away". Complications ensue as Kyra, caught off-guard by Castle's reappearance in her life, wonders if she's marrying the right guy. With the nuptials forestalled and the entire wedding party under suspicion, Beckett questions Castle's ability to be objective about the case. But when it looks to Beckett like Castle and Kyra might rekindle their romance, her judgment may be compromised as well.
Chuck must use his relationship with Awesome to protect a visiting dictator, Premier Goya, who is the target of an assassination. While Awesome is excited about the prospect of being a spy, Chuck is more concerned about Awesome and Ellie's safety.
A teenage girl pronounced brain dead wakes up in the middle of the operation to remove her organs... speaking numbers in Russian. When the Navy confirms that the numbers are nuclear launch codes and a missing officer named Rusk knows them, the search is on for the missing man.
When drug dealer Mickey mysteriously collapses while negotiating a sale, his partner-in-crime, Eddie, accompanies him to Princeton Plainsboro for treatment. But with a major deal pending, Mickey is not forthcoming with the necessary personal information the team needs to treat him. As Mickey's condition worsens, the team resorts to old-fashioned detective work to solve the case. Meanwhile, House and Wilson compete for the affection of a new neighbor, and Chase, Thirteen and Taub attempt to play a practical joke on Foreman.
Susan turns up the heat for Mike, Bree learns it won't be easy to undo the hurt she's caused Orson, Lynette discovers Tom's true intentions, and Gaby is forced to examine feelings she's suppressed about her heritage.
As Ming gets ready to proceed with her plans for artificial insemination, her husband Chen, is stressed and fantasizing about street races and infidelity. The sperm donor, Fitz, their medical school classmate and Ming's former boyfriend, is considering reinstatement at the hospital which stirs up a lot of unresolved issues. His return would also create more tension between the trio since he wouldn't be an absentee donor after all, but working alongside the couple every day.
The 2005 murder of an Army recruiter who was killed just two days before his scheduled deployment to Iraq is reinvestigated after a soldier comes forward with new evidence.
Border Patrol Agents William Ortiz and Eduardo Berlanga try to intercept a pickup truck filled with people who have crossed illegally from Mexico. When they reach the vehicle, they realize that two of the passengers are young twin girls. The situation heats up when they learn that the man claiming to be their father apparently is not being truthful.
A divorced dad at Paige's school piques Sarah's interest, while Justin uncovers the key to his learning challenges. Meanwhile, Nora reunites with her eyes wide open.
Krusty grudgingly adds a pretty, singing cohost named Princess Penelope to his show in order to attract more female viewers. Girls love her, and ratings improve, but Bart and Milhouse want to get the show back to the way it was. The situation gets more complicated when Krusty and Penelope fall in love and decide to get married. Meanwhile, Homer, Lenny, and Carl consider working at a competing nuclear plant when Mr. Burns cuts off their daily doughnut service.
Chuck gets a new mission when Sarah's best friend Carina comes through town with her fiancé Karl. Things get complicated when Chuck wants to hash out his and Sarah's relationship problems while they're on the mission. Meanwhile, Morgan finds himself in trouble when he lies to Jeff and Lester.
As the upgraded Intersect, Chuck trains to become a full-fledged spy but hits rock bottom when he flunks out of spy school and loses Sarah in the process. Meanwhile, Morgan comes home from Benihana School to help Chuck get over Sarah.