Susan learns that she is expecting a child while Bree continues to fake her own pregnancy. Gabrielle begins an affair with her ex-husband, Carlos and Lynette tries to conceal her cancer from her friends and children. The episode also introduces Katherine Mayfair, Susan's old friend who returns to the neighborhood after being away for 12 years.
A freak accident gives Homer an operatic singing voice, and he becomes a star at the Springfield Opera. But with fame and fortune comes a price: He's continually bothered by fans, an obsessed woman in particular.
Things are really beginning to heat up for Dexter: Doakes' suspicions about him are growing, his victims are escaping, and his body dump site has been found. Meanwhile Paul is troubling Rita over the missing shoe and Debra is going through trauma over the Ice Truck killer incident.
Toki Wartooth is fed up playing in the shadow of Skwisgaar's lead guitar. Under the tutelage of a crusty old guitar master, Toki learns that the heart, too, has strings.
Carly's grandfather comes for a visit and is appalled by Spencer's unusual behavior, so he questions Spencer's ability to be in charge. Carly must convince him that Spencer is capable of being her guardian.
After a deceased relative of Zoey's sends her tons of boxes of ribs, Zoey, Chase, Micheal, and Logan agree to have a rib cook-off. After a fierce feud between Micheal and Logan, they decide to compete against each other with Zoey on Micheal's team, and Chase on Logan's. Quinn accidentally blows Mark's eyebrows off in an experiment gone awry.
When Ben accidentally breaks Gwen's laptop, he participates in the "Ultimate Wrestling Competition" as Four Arms to get the prize money for a new laptop to replace Gwen's broken one.
Batman and Robin must battle Superman, who is under Lex Luthor's mind control, as the villain plans to launch a wave of robots and take over the world's armies.
Imperiex begins his conquest of the 31st century by freeing the Legion's greatest enemies from prison. The team must look to Superman in the 21st century for help, and Superman comes to the future only to meet his 41st century clone, Kell-El.
When Kiwi's mindless destruction becomes too much for the group to bear, they force Odd to keep him at the factory. As Odd drops him off, XANA possesses Jeremie's Kiwi Two robot, turning it into an army of self-replicating attack dogs. The dogs attack Yumi and Ulrich, among other children, during Jim's Pencak Silat class. After Aelita deactivates the tower and a return trip erases the incident, the group decides that the regular Kiwi isn't that bad, after all.
Tom and friends face their greatest Chaotic challenge ever – the all-powerful, all-terrifying, all-destructive Allmageddon Attack. The only hope to combat this fearsome force lies in a crazed creature named Hoton. Can our heroes find a way to stop the unstoppable before Peyton gets Allmageddoned? Little do they know, Peyton has a plan to beat it.
In order to celebrate Otis' birthday the animals trick Farmer into going to Turnip-Con for the weekend. However his plans hit a snag when that very same weekend the Beady's nephew, Eugene, comes for a visit.
During a confrontation with Diablo, Johnny is exposed to a potion that makes him more powerful. Unfortunately, the potion also begins to turn him evil.
After Johnny and Dukey send Bumper packing, they start to come against each other in a game of "Say Uncle".
Yeah, Kenichi’s a total wimp. He’s always getting picked on and doesn’t have a lot of friends to stick up for him. The guy needs motivation if he hopes to graduate in one piece. Well, Miu’s the perfect motivation. She’s hot, she accepts him, and she just so happens to live at a dojo with six martial arts masters. You could say fate has led Kenichi to their door, or you could say he was just following the hottie. Either way, he’s about to get whipped into serious shape. If he can survive some hard-core training, he might survive another day at school. He might even score with Miu. Yeah, you could call Kenichi a wimp. But let’s go with underdog instead.
When Guy's daughter Chloe gets appendicitis, Lee and Tim are left looking after her son Dillon while Guy and Lucy visit her. While in their care, Dillon swallows a subbuteo football and Lee and Tim have problems locating it, and try to think of ways to get it out of his body. However, it later turns out Dillon did not swallow it after all. Lucy is worried about the age gap between her and Guy.
Jimmy is invited out to meet Siobhan's father. His nerves aren't helped when Diana decides to tag along. Diana and Siobhan's dad soon hit it off but when Diana wants out of the relationship it is up to Jimmy to help her end things.
When a series of vampire-style murders plague L.A., immortal investigator Mick St. John sets out to find the culprits and re-connects with a woman, Internet reporter Beth Turner, from his past at a crime scene.