New players and new blood leads to big pots. Sammy Farha, Eli Elezra, Shawn Sheikhan, and Todd Brunson join Daniel Negreanu, Doyle Brunson, Jennifer Harman, and Barry Greenstein for another High Stakes Poker cash game.
At his high school reunion, Peter tries to impress his fellow classmates. When Peter, heading for the bathroom, charges through the crowd of people, impresses quarterback Tom Brady, who offers Peter a spot on the New England Patriots. Meanwhile, Brian owes Stewie money, after Stewie becomes a sports bookie.
Jude starts a long-distance relationship with a girl from Australia. Meanwhile, Wyatt gets fired from Underground Video, and starts to work at "Burger McFlipsters". (Alan Park guest stars as Tim.)
Macy is stunned when he discovers that a body from a gang related shooting is his daughters boyfriend. When a gun from the crime scene returns with Abby's prints on it, the entire team focuses on finding the missing girl.
The girls can no longer relax on the boy's dorm roof, thanks to Logan. To solve this problem, they must prove that boys can act the same with girls around. So, they transform Lola into 'Steve' and Steve goes to live with Chase and Logan.
In order to raise money to save the Tom Landry Middle School baseball program, Hank invites a Harlem Globetrotters-type softball team to compete against his community league Arlen Zephyrs. But Hank ruins the show by deciding to take the game seriously.
After Bart steals a key from Principal Skinner's office and gets himself into hot water, Marge and Homer send him to a behavior modification camp.
A broke Francis gets talked into getting a real job by Dewey, but one of Francis' rocker friends decides to offer him the position of tour manager of his band instead. Back home, Hal takes over the college recruiters, which Malcolm refuses to meet with, and treats each one as a suitor. However, Hal's plans are ruined when Malcolm chooses to go Harvard.
All the nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves. George refuses to cross the picket line and finally joins the nurses on their strike while Alex, Cristina, Izzie and Meredith meets Bailey's stand-in: Dr. Cindy Aaron, the complete opposite of Miranda Bailey. Izzie agrees to work on a difficult pregnancy case with Addison, while Cristina and Alex are in the pit attending to a young married woman with a real bad case of rash. Meredith happens on an old woman that she needs to intubate and then learns she was DNR.
The squad is ordered to evict the residents of an orphanage. Sergio is conflicted over his attraction to Anna. Meanwhile, Terry looks into why Bo has stopped receiving his military pay.
Orel Puppington learns that God doesn't look kindly on the wasteful. After lessons from Coach Stopframe and his father, he sets out with two goals in mind. Orel must stop his own wastefulness, and ensure he doesn't end up the failure his father predicts of him. Will he succeed, or will he upset the townsfolk once again?
While Tina and Helena attend a documentary screening, Bette leaves for Washington D.C. to speak at a Senate hearing and meets with Senator Barbara Grisham. Attempting to provide for both herself and Moira, Jenny puts her dreams of becoming a writer on hold and starts waitressing at The Planet. Jenny and Moira are also invited to a party hosted by Billie Blaikie where Moira meets like-minded people. Meanwhile, Carmen has to decide whether to give up Shane's opening party in exchange for a once-in-a-lifetime opportunity to DJ at an exclusive VIP party, and Dana plays at a tennis tournament and declares her love for Lara in front of TV cameras.
After receiving a hefty bonus from work, Stan buys extravagant gadgets while Francine pleads for her dream kiosk. Upset about his lack of support, Francine opens a muffin shop without his approval and gives Stan a taste of life without a housewife. In a desperate move, Stan puts Klaus' brain back into a human body – only to discover it was a huge mistake as Klaus tries to win over Francine. Meanwhile, Steve is convinced he's a teen wolf after watching a horror film.
The series focuses on an eccentric motley crew that is the Smith family and their three housemates: Father, husband, and breadwinner Stan Smith; his better half housewife, Francine Smith; their college-aged daughter, Hayley Smith; and their high-school-aged son, Steve Smith. Outside of the Smith family, there are three additional main characters, including Hayley's boyfriend turned husband, Jeff Fischer; the family's man-in-a-goldfish-body pet, Klaus; and most notably the family's zany alien, Roger, who is "full of masquerades, brazenness, and shocking antics."
In order to re-organize the seed collection of famous botanist, Edwin Pargeter, Rosemary and Laura are called in by the current generation of Pargeters to help with the task. Their task is daunting, and it's not helped when a mysterious Chilean man is found dead in the back garden of the Pargeters' house. As they try to work out who the man was, they soon discover that something in Edwin's seeds is quite valuable, and that someone is out to get them, no matter the cost...
Ben is pursued by three bounty hunters sent by Vilgax to steal the Omnitrix.
Josie finds herself seemingly trapped within an alternate dimension which she inadvertently created by taking Victor's power source, the floating chi ball, to prevent a future she believed to be her fault and not the destined timeline.
Josh nabs a student teaching job in Megan’s classroom where Drake discovers an amazing kid drummer. But when the class revolts against teen taskmaster Josh, Drake rushes in to help Megan discredit him -- perchance to snare the drummer for his band.