While House's staff tries to diagnose a woman whose uncontrollable muscle flailing caused her to crash her car, House and Stacy try to resolve their relationship issues once and for all. Cameron refuses to take her HIV test, wary of the results.
Sam has a premonition in which a man is killed, but the murder is made to look like a suicide. Sam convinces Dean that they must investigate the case, but the two are puzzled when they fail to find anything that indicates that the death was supernatural in nature. That is, until they find out that Max, the reclusive son of the first victim, has been using his recently acquired power of telekinesis to kill the family members that once abused him. Sam also discovers Max's mother was killed by the same fiery demon that took his own mom.
Via a bug planted in the clubhouse, Kavanaugh monitors the Strike Team as they investigate an illegal prescription drug ring that is proving to be deadly for the people of Farmington. While working on a missing person’s case, Dutch attempts find out what Claudette is hiding.
Mayor Meanswell is once again getting ready to present the Person of the Year trophy to Sportacus, but can't seem to keep it a secret that Sportacus is the winner. When he hears that Sportacus is winning again, Robbie decides to put a stop to it. Considering the past failures of his evil plans, he decides to hit Sportacus with several of his past failures, hoping that they'll combine into a success.
The Gallagher clan can't believe it when Carl starts to bring money into the household - but his mini-enterprise involves growing cannabis for the Maguires and the police are quick to bust him. Lip is jealous when Mandy gets a new boyfriend and he later discovers that she was the brains behind Carl's business.
Pablo's past comes back to haunt him when someone comes to Raintree and tells him he has to train his horse; Meanwhile, Matt takes on a new job, which upsets Jean to no end. Isabelle stirs up more trouble, and does her best to prevent Ken and Junior from reconciling.
An urban legend becomes true when Danny finds a guest in an ice filled bathtub missing a kidney. To avoid bad press, the lawyers want to pay him for his silence, but Danny and Mike have other plans and start to investigate a possible scam. Ed helps Sam treat a whale who suffers from really sweaty hands, which is starting to scare the other guests away. Jimmie Johnson comes over to the Montecito to be the final judge of a car convention, in which Delinda for one is participating in.
Doug and his pals rent an apartment to use as a secret hang-out. Meanwhile, Carrie goes to great lengths to please her newest client, Kirstie Alley.
Sam and Gene go undercover in a local pub to solve the murder of a local Manchester United fan. As Gene looks like he's set to drink the pub dry, Sam worries about their chances of finding the killer before Saturday's big match. With the press using the murder to fuel the flames of hate between rival fans, Sam is under pressure to solve the murder before the tensions destroy the community.
Nothing goes right for Daniel Negreanu, and it's all fun and games until Sammy Farha shows up. Eli Elezra, Jerry Buss, Shawn Sheikhan, Todd Brunson, Barry Greenstein, and Jennifer Harman round out another High Stakes Poker cash game.
Eric Camden, a minister, and his wife Annie deal with the drama of having seven children, ranging from toddlers to adults with families of their own.
Harry loses his cool with 3 swimmers that he's forced to rescue just seconds after warning them not to swim in a dangerous area. However, calling them "imbeciles" and "idiots" puts him in hot water.
When Horatio's nemesis, Walter Resden targets someone close to him, Horatio tries to stop him. Also Eric Delko's relationship with Natalia is tested when she thinks she may be pregnant.
A sportscaster becomes a full-time dad when his ex-wife decides to accept a job out of the country and his teenage daughter, Breanna, moves in with him.
Dee Dee receives the opportunity to appear on a sports talk show, only to humiliate herself by falling flat on her face. Mona objects when Spencer and Adam constantly give in to Dalis's petty demands. She finally puts her foot down, with disastrous results.
The J-Spot attracts the attention of a journalist who gives Joan a huge career look. Lynn shares her original compositions. Wayne Brady guest stars.
Jack tracks down a man who has a connection to the terrorists. Logan is forced to grant him immunity in exchange for information on their whereabouts. Mike and Martha argue over Logan's public response to Walt's involvement with the Russians. Lynn is drawn away from his post by a personal crisis as the terrorists come closer to striking against the U.S.
After agreeing to take things slowly and not have sex for a month, Ted and Victoria decide that they have waited long enough.